ArticleMaterials (Basel, Switzerland)2022
Electrochemical Synthesis of Zinc Oxide Nanostructures on Flexible Substrate and Application as an Electrochemical Immunoglobulin-G Immunosensor.
Article in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 38 citations in OpenAlex.
- Detection of Synaptic Vesicle Glycoprotein 2A in Serum Using a Polypyrrole-Functionalized Graphene Oxide Electrochemical Immunosensor.Nanomaterials (Basel, Switzerland) · 2026Article
- Revolutionizing healthcare with nanosensor technology.RSC advances · 2025Review
- The Application of Ultrasound Pre-Treatment in Low-Temperature Synthesis of Zinc Oxide Nanorods.Materials (Basel, Switzerland) · 2024Article
- Molecularly imprinted polymer-based extended-gate field-effect transistor chemosensors for selective determination of antiepileptic drug.Mikrochimica acta · 2024Article
- Metal Oxides Nanomaterials and Nanocomposite-Based Electrochemical Sensors for Healthcare Applications.Biosensors · 2023Review
- Recent Advances in Synthesis and Application of Metal Oxide Nanostructures in Chemical Sensors and Biosensors.Nanomaterials (Basel, Switzerland) · 2022Review
- Behavior of Calcium Phosphate-Chitosan-Collagen Composite Coating on AISI 304 for Orthopedic Applications.Polymers · 2022Article
- Electrochemical Quantification of HMicromachines · 2022Article
- Development and testing of zinc sulfate and zinc oxide nanoparticle-coated urea fertilizer to improve N and Zn use efficiency.Frontiers in plant science · 2022Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Immunoglobulin G (IgG), a type of antibody, represents approximately 75% of serum antibodies in humans, and is the most common type of antibody found in blood circulation. Consequently, the development of simple, fast and reliable systems for IgG detection, which can be achieved using electrochemical sandwich-type immunosensors, is of considerable interest. In this study we have developed an immunosensor for human (H)-IgG using an inexpensive and very simple fabrication method based on ZnO nanorods (NRs) obtained through the electrodeposition of ZnO. The ZnO NRs were treated by electrodepositing a layer of reduced graphene oxide (rGO) to ensure an easy immobilization of the antibodies. On Indium Tin Oxide supported on Polyethylene Terephthalate/ZnO NRs/rGO substrate, the sandwich configuration of the immunosensor was built through different incubation steps, which were all optimized. The immunosensor is electrochemically active thanks to the presence of gold nanoparticles tagging the secondary antibody. The immunosensor was used to measure the current density of the hydrogen development reaction which is indirectly linked to the concentration of H-IgG. In this way the calibration curve was constructed obtaining a logarithmic linear range of 10-1000 ng/mL with a detection limit of few ng/mL and good sensitivity.
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