Evidence map›Paper›PMID 35160311›Full record

ReviewJournal of clinical medicine2022

Viscoelastic Hemostatic Assays: A Primer on Legacy and New Generation Devices.

Oksana Volod, Connor M Bunch, Nuha Zackariya, Ernest E Moore, Hunter B Moore, Hau C Kwaan, Matthew D Neal, Mahmoud D Al-Fadhl, Shivani S Patel, Grant Wiarda and 10 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
14.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it, 99 citations in OpenAlex.

  1. Guideline
  2. Trial
  3. An Automated Microfluidic System for Haemostasis Assessment in Cirrhosis With Thrombocytopenia.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Article
  4. Article
  5. Observational
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 8 institutions in 2 countries.

Oksana VolodDepartment of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.ORCID 0000-0001-6285-7585
Connor M BunchDepartment of Internal Medicine, Saint Joseph Regional Medical Center, Mishawaka, IN 46545, USA.ORCID 0000-0002-8566-7001
Nuha ZackariyaDepartment of Internal Medicine, Indiana University School of Medicine South Bend Campus, Notre Dame, IN 46617, USA.
Ernest E MooreDepartment of Surgery, Ernest E. Moore Shock Trauma Center at Denver Health and University of Colorado Health Sciences Center, Denver, CO 80204, USA.ORCID 0000-0002-0419-4848
Hunter B MooreDepartment of Surgery, Ernest E. Moore Shock Trauma Center at Denver Health and University of Colorado Health Sciences Center, Denver, CO 80204, USA.
Hau C KwaanDivision of Hematology and Oncology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.ORCID 0000-0002-5733-6248
Matthew D NealPittsburgh Trauma Research Center, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.
Mahmoud D Al-FadhlDepartment of Internal Medicine, Saint Joseph Regional Medical Center, Mishawaka, IN 46545, USA.ORCID 0000-0002-3481-1966
Shivani S PatelDepartment of Internal Medicine, Saint Joseph Regional Medical Center, Mishawaka, IN 46545, USA.
Grant WiardaDepartment of Internal Medicine, Saint Joseph Regional Medical Center, Mishawaka, IN 46545, USA.ORCID 0000-0002-1561-6161
Hamid D Al-FadhlDepartment of Internal Medicine, Saint Joseph Regional Medical Center, Mishawaka, IN 46545, USA.
Max L McCoyDepartment of Internal Medicine, Saint Joseph Regional Medical Center, Mishawaka, IN 46545, USA.ORCID 0000-0002-2143-7944
Anthony V ThomasDepartment of Internal Medicine, Indiana University School of Medicine South Bend Campus, Notre Dame, IN 46617, USA.ORCID 0000-0001-9520-9306
Scott G ThomasDepartment of Trauma Surgery, Memorial Leighton Trauma Center, Beacon Health System, South Bend, IN 46601, USA.
Laura GillespieDepartment of Quality Assurance and Performance Improvement, Saint Joseph Regional Medical Center, Mishawaka, IN 46545, USA.
Rashid Z KhanDepartment of Hematology, Michiana Hematology Oncology, Mishawaka, IN 46545, USA.
Mahmud ZamlutDepartment of Critical Care Medicine, Saint Joseph Regional Medical Center, Mishawaka, IN 46545, USA.
Peter KamphuesDepartment of Quality Assurance and Performance Improvement, Saint Joseph Regional Medical Center, Mishawaka, IN 46545, USA.
Dietmar FriesDepartment of Anesthesiology and Critical Care Medicine, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Mark M WalshDepartment of Internal Medicine, Saint Joseph Regional Medical Center, Mishawaka, IN 46545, USA.ORCID 0000-0002-5795-1144
St. Joseph Regional Medical Center · USDenver Health Medical Center · USIndiana University School of MedicineBeacon Health System · USCedars-Sinai Medical Center · USInnsbruck Medical University · ATNorthwestern University · USUniversity of Pittsburgh Medical Center · US

Funding

Mechanistic Elucidation and Targeted Therapy of Platelet Dysfunction After TraumaR35GM119526 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI NEAL, MATTHEW D · 2016 to 2025
$3.9M
NIGMS NIH HHS R35 GM119526
6 · The paper itself

Abstract

Viscoelastic hemostatic assay (VHAs) are whole blood point-of-care tests that have become an essential method for assaying hemostatic competence in liver transplantation, cardiac surgery, and most recently, trauma surgery involving hemorrhagic shock. It has taken more than three-quarters of a century of research and clinical application for this technology to become mainstream in these three clinical areas. Within the last decade, the cup and pin legacy devices, such as thromboelastography (TEG

Indexed as

coagulopathyCOVID-19fibrinogenhemorrhageheparinpersonalized medicinerotational thromboelastometrythromboelastographythrombosis

Identifiers

PMID35160311
PMCPMC8836477
OpenAlexW4210917725

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.