Evidence map›Paper›PMID 35160305›Full record

ArticleJournal of clinical medicine2022

Effects of the Dental Caries Preventive Procedure on the White Spot Lesions during Orthodontic Treatment-An Open Label Randomized Controlled Trial.

Yudai Shimpo, Yoshiaki Nomura, Toshiko Sekiya, Chihiro Arai, Ayako Okada, Kaoru Sogabe, Nobuhiro Hanada, Hiroshi Tomonari

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05979805 (Effectiveness of Motivational Interviewing and Conventional Oral Health Education), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05979805 narecruitingnot on this mapstarted 2024, after this paper: background citation

Effectiveness of Motivational Interviewing and Conventional Oral Health Education (OHEc) Versus OHEc in the Prevention and Control of Dental Caries and Gingivitis in Subjects With Fixed Orthodontic Appliances. A Randomized Controlled Trial

TypeinterventionalSponsorUniversidad Nacional de ColombiaRan2024 to 2026Enrolled94ConditionsDental Caries, Tooth Demineralization, GingivitisArmsConventional Educational interventions, Motivational intervention
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. White Spots: Prevention in Orthodontics-Systematic Review of the Literature.International journal of environmental research and public health · 2023
    Pooled it
  2. Review
  3. Review
  4. Biomaterial investigations in dentistry · 2023
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Yudai ShimpoDepartment of Orthodontics, Tsurumi University School of Dental Medicine, Yokohama 230-8501, Japan.
Yoshiaki NomuraDepartment of Translational Research, Tsurumi University School of Dental Medicine, Yokohama 230-8501, Japan.ORCID 0000-0002-0814-0572
Toshiko SekiyaDepartment of Orthodontics, Tsurumi University School of Dental Medicine, Yokohama 230-8501, Japan.
Chihiro AraiDepartment of Orthodontics, Tsurumi University School of Dental Medicine, Yokohama 230-8501, Japan.
Ayako OkadaDepartment of Operative Dentistry, Tsurumi University School of Dental Medicine, Yokohama 230-8501, Japan.
Kaoru SogabeDepartment of Translational Research, Tsurumi University School of Dental Medicine, Yokohama 230-8501, Japan.
Nobuhiro HanadaInternational Photocatalyst Research Institute, University of Shanghai for Science and Technology, 516 Jungong Road, Shanghai 200093, China.
Hiroshi TomonariDepartment of Orthodontics, Tsurumi University School of Dental Medicine, Yokohama 230-8501, Japan.
Tsurumi University · JPUniversity of Shanghai for Science and Technology · CN

Funding

JSPS KAKENHI 20K10303JSPS KAKENHI 20K18815SECOM Science and Technology Foundation Not applicable
6 · The paper itself

Abstract

(1) Background: The aim of this study was to assess the preventive effect of tooth surface disinfection treatment, in addition to fluoride application, during fixed orthodontic treatment. (2) Methods: An open label randomized control trial for the evaluation of the dental caries preventive procedure was performed for the patients with high caries risk who had been visited at Department of Orthodontics, Tsurumi University Dental Hospital for orthodontics treatment. The follow-up period was six months. White spot lesions (WSLs) were evaluated by quantitative light-induced fluorescence (QLF). Cariogenic bacteria were monitored and evaluated by bacterial culture. In addition, the oral microbiome was evaluated by a next-generation sequence (NGS). (3) Results: By the mixed effect modeling, tooth surface disinfection treatment significantly reduced cariogenic bacteria and all parameters obtained by QLF. (4) Conclusions: Tooth surface disinfection treatment, in addition to PMTC and fluoride application, were effective for dental caries prevention and keeping a healthy microbiome during orthodontic treatment.

Indexed as

fixed orthodontic treatmentmixed effect modeloral microbiomequantitative light-induced fluorescencetooth surface disinfection

Identifiers

PMID35160305
PMCPMC8836958
OpenAlexW4210734216

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.