Evidence map›Paper›PMID 35160248›Full record

ArticleJournal of clinical medicine2022

External Validation of a Novel Comprehensive Trifecta System in Predicting Oncologic and Functional Outcomes of Partial Nephrectomy: Results of a Multicentric Series.

Umberto Anceschi, Rocco Simone Flammia, Daniele Mattevi, Antonio Tufano, Aldo Brassetti, Maria Consiglia Ferriero, Gabriele Tuderti, Leonardo Misuraca, Alfredo Maria Bove, Riccardo Mastroianni and 8 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 1 country.

Umberto AnceschiDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.
Rocco Simone FlammiaDepartment of Maternal-Child and Urologic Sciences, Policlinico Umberto I, Sapienza University of Rome, Viale dell'Università 33, 00161 Rome, Italy.ORCID 0000-0002-3129-0544
Daniele MatteviDepartment of Urology, APSS-Santa Chiara Regional Hospital, Largo Medaglie d'Oro 9, 38122 Trento, Italy.
Antonio TufanoDepartment of Maternal-Child and Urologic Sciences, Policlinico Umberto I, Sapienza University of Rome, Viale dell'Università 33, 00161 Rome, Italy.
Aldo BrassettiDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.ORCID 0000-0001-9643-8979
Maria Consiglia FerrieroDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.
Gabriele TudertiDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.ORCID 0000-0003-4480-9090
Leonardo MisuracaDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.
Alfredo Maria BoveDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.
Riccardo MastroianniDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.
Davide MarsilianiEmergency Medicine Department, Presidio Ospedaliero G.B. Grassi, Via Gian Carlo Passeroni, 28, 00122 Ostia, Italy.
Marco PuglisiDepartment of Urology, APSS-Santa Chiara Regional Hospital, Largo Medaglie d'Oro 9, 38122 Trento, Italy.
Tommaso CaiDepartment of Urology, APSS-Santa Chiara Regional Hospital, Largo Medaglie d'Oro 9, 38122 Trento, Italy.ORCID 0000-0002-7234-3526
Costantino LeonardoDepartment of Maternal-Child and Urologic Sciences, Policlinico Umberto I, Sapienza University of Rome, Viale dell'Università 33, 00161 Rome, Italy.
Michele GallucciDepartment of Maternal-Child and Urologic Sciences, Policlinico Umberto I, Sapienza University of Rome, Viale dell'Università 33, 00161 Rome, Italy.
Gianni MalossiniDepartment of Urology, APSS-Santa Chiara Regional Hospital, Largo Medaglie d'Oro 9, 38122 Trento, Italy.
Lorenzo Giuseppe LucianiDepartment of Urology, APSS-Santa Chiara Regional Hospital, Largo Medaglie d'Oro 9, 38122 Trento, Italy.
Giuseppe SimoneDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.ORCID 0000-0002-4868-9025
Istituti di Ricovero e Cura a Carattere Scientifico · ITOspedale Santa Chiara · ITPoliclinico Umberto I · ITPresidio Ospedaliero · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo validate a novel trifecta for evaluating outcomes of partial nephrectomy (PN) on a multicentric dataset.

methodsBetween 2007 and 2020, three renal cancer databases were queried for patients with solitary renal masses who underwent PN (n = 649). Trifecta was estimated for overall cohort and contributing centers. Overall survival (OS), cancer-specific survival (CSS) and end-stage renal disease (ESRD) probabilities were assessed by Kaplan-Meier. Cox regression was used to identify predictors of OS, CSS, ESRD. For all analyses, a

resultsAt a median follow-up of 22.7 months (IQR 12.5-76.5) overall trifecta was 76.7% [Centre A; (n = 230; 68.6%), B (n = 68; 77.3%), C (n = 200; 88.4%);

conclusionsOn external validation, trifecta was an independent predictor of all PN endpoints, regardless of hilar control and ischemia duration.

Indexed as

end-stage renal disease (ESRD)ischemiapartial nephrectomysurvivaltrifecta

Identifiers

PMID35160248
PMCPMC8837057
OpenAlexW4210597633

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.