Evidence map›Paper›PMID 35160247›Full record

ArticleJournal of clinical medicine2022

Surgical Quality, Antihypertensive Therapy, and Electrolyte Balance: A Novel Trifecta to Assess Long-Term Outcomes of Adrenal Surgery for Unilateral Primary Aldosteronism.

Umberto Anceschi, Marilda Mormando, Cristian Fiori, Orazio Zappalà, Bernardino De Concilio, Aldo Brassetti, Alessandro Carrara, Maria Consiglia Ferriero, Gabriele Tuderti, Leonardo Misuraca and 9 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 6 institutions in 2 countries.

Umberto AnceschiDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.
Marilda MormandoOncologic Endocrinology Unit, IRCCS "Regina Elena" National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.
Cristian FioriDepartment of Urology, AOU San Luigi Gonzaga, Regione Gonzole, 10, 10043 Orbassano, Italy.
Orazio ZappalàDepartment of General Surgery, Santa Chiara Regional Hospital, APSS, Largo Medaglie d'Oro 9, 38122 Trento, Italy.
Bernardino De ConcilioDepartment of Urology, San Bassiano Hospital, ULSS 7 Pedemontana, Via dei Lotti, 40, 36061 Bassano del Grappa, Italy.
Aldo BrassettiDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.ORCID 0000-0001-9643-8979
Alessandro CarraraDepartment of General Surgery, Santa Maria del Carmine Hospital, APSS, Corso Verona 4, 38068 Rovereto, Italy.
Maria Consiglia FerrieroDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.ORCID 0000-0001-5188-8001
Gabriele TudertiDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.ORCID 0000-0003-4480-9090
Leonardo MisuracaDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.
Alfredo Maria BoveDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.
Riccardo MastroianniDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.ORCID 0000-0003-3708-2209
Alfonsina ChiefariOncologic Endocrinology Unit, IRCCS "Regina Elena" National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.
Marialuisa AppetecchiaOncologic Endocrinology Unit, IRCCS "Regina Elena" National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.ORCID 0000-0002-2124-1335
Giuseppe TironeDepartment of General Surgery, Santa Chiara Regional Hospital, APSS, Largo Medaglie d'Oro 9, 38122 Trento, Italy.
Francesco PorpigliaDepartment of Urology, AOU San Luigi Gonzaga, Regione Gonzole, 10, 10043 Orbassano, Italy.ORCID 0000-0001-8567-6795
Antonio CeliaDepartment of Urology, San Bassiano Hospital, ULSS 7 Pedemontana, Via dei Lotti, 40, 36061 Bassano del Grappa, Italy.
Michele GallucciDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.
Giuseppe SimoneDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.ORCID 0000-0002-4868-9025
Istituti di Ricovero e Cura a Carattere Scientifico · ITNational Cancer Institute · MYOspedale San Bassiano · ITOspedale San Luigi Gonzaga · ITOspedale Santa Chiara · ITOspedale Santa Maria · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo propose a trifecta that summarizes endpoints and predicts their maintenance after adrenalectomy (

methodsTrifecta was defined as coexistence of: ≥50% antihypertensive therapeutic intensity score reduction (∆TIS), no hypokalemia at 3 months, and no Clavien grade 2-5. Logistic regression was used to identify predictors of trifecta. Probability of clinical, biochemical, and simultaneous success according to trifecta were assessed by Kaplan-Meier. Cox regression was used to identify predictors of long-term clinical, biochemical, and simultaneous success. For all analyses, a two-sided

resultsSimultaneous success rate was 50%. On multivariable analysis, TIS was an independent predictor of trifecta achievement (HR 3.28; 95% CI 1.07-10.9;

conclusionsTrifecta and AS are independent predictors of either long-term complete clinical, biochemical, or combined success after adrenalectomy for UPA.

Indexed as

adrenalectomyConn’s syndromePASOprimary aldosteronismtrifecta

Identifiers

PMID35160247
PMCPMC8836466
OpenAlexW4210290440

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.