ArticleJournal of clinical medicine2022
Prematurity and Long-Term Respiratory Morbidity-What Is the Critical Gestational Age Threshold?
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 27 citations in OpenAlex.
- Respiratory disease in cerebral palsy: the overlooked impact of neonatal lung disease.BMJ paediatrics open · 2026Article
- Breaking the Cycle of Preterm Birth: A Prospective Cohort Study on Maternal Stress and Recurrent Preterm Birth.BJOG : an international journal of obstetrics and gynaecology · 2026Article
- Nationwide study of respiratory-related hospitalisations and deaths in preterm children in Brazil: a registry-based study.Respiratory research · 2025Article
- Two-year outcomes after selective early treatment of patent ductus arteriosus with ibuprofen in preterm babies: follow-up of Baby-OSCAR-a randomised controlled trial.EClinicalMedicine · 2025Article
- Article
- Outpatient Respiratory Outcomes in Extremely Preterm Children During the First 3 Years of Life.Pediatric pulmonology · 2025Article
- IgA Vasculitis (Henoch-Schönlein Purpura) in a Seven-Year-Old Female Child With Recurrent Respiratory Infections.Cureus · 2025Article
- A Retrospective Multicenter Stratified Study on Perinatal Factors Influencing Neonatal Mortality in Preterm Infants in Kazakhstan.International journal of pediatrics · 2025Article
- Functional MRI assessment of the lungs in fetuses that deliver very Preterm: An MRI pilot study.European journal of obstetrics, gynecology, and reproductive biology · 2024Article
- Twins vs singletons-Long-term health outcomes.Acta obstetricia et gynecologica Scandinavica · 2023Article
- Pediatric Pulmonology Training in India: Current Status and Future Directions.Indian journal of pediatrics · 2023Review
- "Advances in Preterm Delivery"-How Can We Advance Further?Journal of clinical medicine · 2022Article
- The Association between Gestational Age and Risk for Long Term Ophthalmic Morbidities among Offspring Delivered in Different Preterm Subgroups.Journal of clinical medicine · 2022Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Respiratory morbidity is a hallmark complication of prematurity. Children born preterm are exposed to both short- and long-term respiratory morbidity. This study aimed to investigate whether a critical gestational age threshold exists for significant long-term respiratory morbidity. A 23-year, population-based cohort analysis was performed comparing singleton deliveries at a single tertiary medical center. A comparison of four gestational age groups was performed according to the WHO classification: term (≥37.0 weeks, reference group), moderate to late preterm (32.0-36.6 weeks), very preterm (28.0-31.6 weeks) and extremely preterm (24.0-27.6 weeks). Hospitalizations of the offspring up to the age of 18 years involving respiratory morbidities were evaluated. A Kaplan-Meier survival curve was used to compare cumulative hospitalization incidence between the groups. A Cox proportional hazards model was used to control for confounders and time to event. Overall, 220,563 singleton deliveries were included: 93.6% term deliveries, 6% moderate to late preterm, 0.4% very preterm and 0.1% extremely preterm. Hospitalizations involving respiratory morbidity were significantly higher in children born preterm (12.7% in extremely preterm children, 11.7% in very preterm, 7.0% in late preterm vs. 4.7% in term,
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