Evidence map›Paper›PMID 35160122›Full record

ReviewJournal of clinical medicine2022

Efficacy and Toxicity of Classical Immunosuppressants, Retinoids and Biologics in Hidradenitis Suppurativa.

Kinnor Das, Steven Daveluy, George Kroumpouzos, Komal Agarwal, Indrashis Podder, Katherine Farnbach, Alex G Ortega-Loayza, Jacek C Szepietowski, Stephan Grabbe, Mohamad Goldust

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05580029 (Open Label Prospective Trial of Fractional Ablative CO 2 Resurfacing With Laser- Facilitated Steroid Delivery in Patients With Mild to Moderate Hidradenitis Suppurativa.), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05580029 early_phase1unknown statusnot on this map

Open Label Prospective Trial of Fractional Ablative CO 2 Resurfacing With Laser- Facilitated Steroid Delivery in Patients With Mild to Moderate Hidradenitis Suppurativa.

TypeinterventionalSponsorUniversity of Southern CaliforniaRan2022 to 2023Enrolled10ConditionsScar, Hidradenitis SuppurativaArmsTriamcinolone Topical, Fractional Ablative CO2 Therapy, EMLA 5% cream
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
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  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 5 countries.

Kinnor DasDepartment of Dermatology Venereology and Leprosy, Silchar Medical College, Silchar 788014, India.ORCID 0000-0002-1719-3465
Steven DaveluyDepartment of Dermatology, Wayne State University, Detroit, MI 48202, USA.
George KroumpouzosDepartment of Dermatology, Alpert Medical School of Brown University, Providence, RI 02903, USA.ORCID 0000-0002-5915-4640
Komal AgarwalDepartment of Dermatology, CNMC, Kolkata 700014, India.
Indrashis PodderDepartment of Dermatology, Venereology and Leprosy, College of Medicine and Sagore Dutta Hospital, Kolkata 700058, India.
Katherine FarnbachDepartment of Dermatology, Oregon Health and Science University, Portland, OR 97239, USA.
Alex G Ortega-LoayzaDepartment of Dermatology, Oregon Health and Science University, Portland, OR 97239, USA.ORCID 0000-0001-5028-9269
Jacek C SzepietowskiDepartment of Dermatology, Venereology and Allergology, Wroclaw Medical University, 50-367 Wroclaw, Poland.ORCID 0000-0003-0766-6342
Stephan GrabbeDepartment of Dermatology, University Medical Center Mainz, 55131 Mainz, Germany.ORCID 0000-0002-6863-8719
Mohamad GoldustDepartment of Dermatology, University Medical Center Mainz, 55131 Mainz, Germany.ORCID 0000-0002-8646-1179
Johannes Gutenberg University Mainz · DEOregon Health & Science University · USBrown University · USCollege of Medicine & Sagore Dutta Hospital · INKolkata Municipal Corporation · INSilchar Medical College and Hospital · INWayne State University · USWroclaw Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hidradenitis suppurativa (HS) is a chronic inflammatory disorder of the apocrine glands characterized by recurrent episodes. Although several therapies exist, none is completely curative. Several immunosuppressives have been studied with encouraging results and targeted approaches. In this review, we highlight the various immunosuppressives used in this condition along with their salient features to enable physicians to choose the correct therapy for their patients. The search of the peer-reviewed literature included clinical trials, scientific reviews, case series, case reports, and guidelines. The literature was identified from electronic databases (MEDLINE and PubMed) through November 2021; additional articles were included from the references of the identified articles.

Indexed as

hidradenitis suppurativaimmunosuppressantstreatment

Identifiers

PMID35160122
PMCPMC8836901
OpenAlexW4210683025

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.