Evidence map›Paper›PMID 35160049›Full record

ArticleJournal of clinical medicine2022

Multimodality Approach to Lymphedema Surgery Achieves and Maintains Normal Limb Volumes: A Treatment Algorithm to Optimize Outcomes.

Peter Deptula, Anna Zhou, Victoria Posternak, Hui He, Dung Nguyen

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05695924 (Prospective Evaluation of Nanofibrillar Collagen Scaffold), which is not on this map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05695924 narecruitingnot on this mapstarted 2023, after this paper: background citation

Prospective Evaluation of Nanofibrillar Collagen Scaffold (BioBridge®) as an Adjunct to Lymph Node Transplant for Upper Extremity Lymphedema

TypeinterventionalSponsorFibralign CorporationRan2023 to 2025Enrolled60ConditionsLymphedema, EdemaArmsBioBridge® Collagen Matrix, Vascularized Lymph Node Transfer (VLNT)
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Biomaterials in the clinical treatment of lymphedema-a systematic review.Journal of vascular surgery. Venous and lymphatic disorders · 2024
    Pooled it
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Etiology and treatment of cancer-related secondary lymphedema.Clinical & experimental metastasis · 2024
    Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Peter DeptulaDivision of Plastic Surgery, Stanford University Medical Center, Stanford, CA 94304, USA.ORCID 0000-0001-6555-0300
Anna ZhouDivision of Plastic Surgery, Stanford University Medical Center, Stanford, CA 94304, USA.
Victoria PosternakDivision of Plastic Surgery, Stanford University Medical Center, Stanford, CA 94304, USA.
Hui HeDivision of Plastic Surgery, Stanford University Medical Center, Stanford, CA 94304, USA.
Dung NguyenDivision of Plastic Surgery, Stanford University Medical Center, Stanford, CA 94304, USA.ORCID 0000-0002-9494-7523
Stanford Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Surgical treatment of advanced lymphedema is challenging and outcomes are suboptimal. Physiologic procedures including lymphaticovenous anastomosis (LVA) and vascularized lymph node transfer (VLNT) improve lymphatic flow but cannot reverse fibrofatty tissue deposition, whereas liposuction removes fibrofatty tissue but cannot prevent disease progression. The adjunctive use of nanofibrillar collagen scaffolds (BioBridge

Indexed as

BioBridgelymphangiogenesislymphaticovenous anastomosislymphedemavascularized lymph node transfer

Identifiers

PMID35160049
PMCPMC8836570
OpenAlexW4210550590

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.