Evidence map›Paper›PMID 35160040›Full record

ArticleJournal of clinical medicine2022

Associated Factors of High Sedative Requirements within Patients with Moderate to Severe COVID-19 ARDS.

Armin N Flinspach, Hendrik Booke, Kai Zacharowski, Ümniye Balaban, Eva Herrmann, Elisabeth H Adam

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Armin N FlinspachDepartment of Anaesthesiology, Intensive Care Medicine and Pain Therapy, Goethe-University Frankfurt, 60590 Frankfurt/Main, Germany.ORCID 0000-0003-2886-8947
Hendrik BookeDepartment of Anaesthesiology, Intensive Care Medicine and Pain Therapy, Goethe-University Frankfurt, 60590 Frankfurt/Main, Germany.ORCID 0000-0002-0227-7367
Kai ZacharowskiDepartment of Anaesthesiology, Intensive Care Medicine and Pain Therapy, Goethe-University Frankfurt, 60590 Frankfurt/Main, Germany.
Ümniye BalabanDepartment of Biostatistics and Mathematical Modelling, Goethe-University Frankfurt, 60590 Frankfurt/Main, Germany.ORCID 0000-0001-8591-4909
Eva HerrmannDepartment of Biostatistics and Mathematical Modelling, Goethe-University Frankfurt, 60590 Frankfurt/Main, Germany.
Elisabeth H AdamDepartment of Anaesthesiology, Intensive Care Medicine and Pain Therapy, Goethe-University Frankfurt, 60590 Frankfurt/Main, Germany.ORCID 0000-0001-5008-6293
Goethe University Frankfurt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coronavirus pandemic continues to challenge global healthcare. Severely affected patients are often in need of high doses of analgesics and sedatives. The latter was studied in critically ill coronavirus disease 2019 (COVID-19) patients in this prospective monocentric analysis. COVID-19 acute respiratory distress syndrome (ARDS) patients admitted between 1 April and 1 December 2020 were enrolled in the study. A statistical analysis of impeded sedation using mixed-effect linear regression models was performed. Overall, 114 patients were enrolled, requiring unusual high levels of sedatives. During 67.9% of the observation period, a combination of sedatives was required in addition to continuous analgesia. During ARDS therapy, 85.1% (

Indexed as

acute respiratory distress syndromecritical carehypnotics and sedativesprone positionpulmonary ventilationsevere acute respiratory syndrome coronavirus 2

Identifiers

PMID35160040
PMCPMC8837042
OpenAlexW4210347699

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.