ArticleJournal of clinical medicine2022
The Combination of Lymph Node Transfer and Excisional Procedures in Bilateral Lower Extremity Lymphedema: Clinical Outcomes and Quality of Life Assessment with Long-Term Follow-Up.
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy of kinesio taping on upper limb volume reduction in patients with breast cancer-related lymphedema: a systematic review of randomized controlled trials.European journal of physical and rehabilitation medicine · 2023Pooled it
- [Advances in intra-abdominal vascularized lymph node transfer for treatment of limb lymphedema].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026Review
- Review
- Surgical Treatment, Rehabilitative Approaches and Functioning Assessment for Patients Affected by Breast Cancer-Related Lymphedema: A Comprehensive Review.Medicina (Kaunas, Lithuania) · 2025Review
- Gastroepiploic Vascularized Lymph Node Transfer for Extremity Lymphedema: Tips and Insights from Extensive Clinical Experience.Medicina (Kaunas, Lithuania) · 2025Article
- The MD Anderson Algorithm for Lymphedema Management.Journal of clinical medicine · 2025Review
- The prognostic effect and mechanism of erysipelas in cancer-associated lymphedema.Scientific reports · 2025Article
- Predictors of the Efficacy of Lymphedema Decongestive Therapy.Medicina (Kaunas, Lithuania) · 2025Review
- Short- and Long-Term Efficacy of Hyperbaric Oxygen Therapy in Irradiated Breast Cancer Patients With Long-Standing Lymphedema: A Prospective Case Series.Cancer reports (Hoboken, N.J.) · 2025Article
- Article
- Modern approaches to lymphatic surgery: a narrative review.Translational breast cancer research : a journal focusing on translational research in breast cancer · 2025Review
- Case Report: Surgical management of primary lymphedema with a novel PROX1 mutation involving upper and lower limbs.Frontiers in genetics · 2025Article
- Skin-derived vascularized lymph node transfer combining with liposuction in stages for bilateral lower extremity lymphedema: a case report.Frontiers in oncology · 2025Article
- Evaluation of the Effectiveness of Active Vitamin D Use in Experimental Rat Lymphedema Model.Medicina (Kaunas, Lithuania) · 2024Article
- Synchronous supraclavicular vascularized lymph node transfer and liposuction for gynecological cancer-related lower extremity lymphedema: A clinical comparative analysis of three different procedures.Journal of vascular surgery. Venous and lymphatic disorders · 2024Article
- Management of Ulcers and Lymphorrhea in Lower Limbs after Charles Procedure via Supermicrosurgery.Plastic and reconstructive surgery. Global open · 2024Article
- Combination of Supramicrosurgical Lymphatico-Venular Anastomosis (sLVA) and Lymph-Sparing Liposuction in Treating Cancer-Related Lymphedema: Rationale for a Regional One-Stage Approach.Journal of clinical medicine · 2024Article
- Aesthetic Rehabilitation Medicine: Enhancing Wellbeing beyond Functional Recovery.Medicina (Kaunas, Lithuania) · 2024Review
- Article
- Editorial for the Special Issue "Vasorum Lymphaticorum: From the Discovery of the Lymphatic System to the New Perspectives in Microsurgical Reconstruction and Patient Rehabilitation".Medicina (Kaunas, Lithuania) · 2024Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBilateral lower extremity lymphedema is a rare and invalidating condition that poses a great challenge to the scientific community, and deeply affects the quality of life (QoL) of affected patients. A combined protocol consisting of lymph node transfer and a reductive method have never been reported for the treatment of this condition, except for small case series with brief follow-up periods.
methodsThis retrospective study analyzed data of 29 patients, mean age 51 ± 17.1 years, who had been diagnosed with bilateral lower extremity lymphedema. Gastroepiploic vascularized lymph node transfer was performed in all the patients, and an excisional procedure was associated according to the clinical stage. Clinical history, circumferential limb measurements, complications, episodes of cellulitis, and responses to the Lymphedema Quality of Life Questionnaire were analyzed.
resultsThe mean follow-up was 38.4 ± 11.8 months. A significant reduction in the episodes of cellulitis per year was observed (
conclusionsAn integrated approach is essential for the treatment of bilateral lower extremity lymphedema: reductive and reconstructive methods are complementary to achieve a successful outcome. Timely treatment and BMI reduction are relevant in order to decrease the number of episodes of cellulitis. An attentive follow-up is necessary to identify recurrence and treat affected patients in time.
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