ArticleJournal of clinical medicine2022
The Analytical Reliability of the Oral Glucose Tolerance Test for the Diagnosis of Gestational Diabetes: An Observational, Retrospective Study in a Caucasian Population.
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Comparing the screening methods for gestational diabetes mellitus before and during the COVID-19 pandemic: A systematic review.Journal of diabetes investigation · 2024Pooled it
- Combined triple screening and BMI models for gestational diabetes prediction.Turkish journal of obstetrics and gynecology · 2026Article
- Effect of Initial Glucose Tolerance Test Response on Pregnancy Outcomes in Type A1 Gestational Diabetes.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- First Trimester Hematological Indices in Gestational Diabetes Mellitus: A Meta-Analysis.Journal of the Endocrine Society · 2025Review
- Enhanced glucose processing in gestational diabetes diagnosis: Effects on health equity and clinical outcomes.Diabetic medicine : a journal of the British Diabetic Association · 2025Observational
- Enzymatic detection of α-hydroxybutyrate, an important marker of insulin resistance, and comparison with LC-MS/MS detection.Practical laboratory medicine · 2024Article
- Sex hormone-binding globulin is a valuable diagnostic indicator of gestational diabetes mellitus.Ghana medical journal · 2024Article
- Non-Invasive Glucose Sensing Technologies and Products: A Comprehensive Review for Researchers and Clinicians.Sensors (Basel, Switzerland) · 2023Review
- Article
- Screening of GDM during COVID pandemic in an Italian setting: comparison between IADPSG and WHO '99 criteria.Diabetology & metabolic syndrome · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Oral Glucose Tolerance Test (OGTT) is currently the gold standard reference test for the diagnosis of gestational diabetes mellitus (GDM). Several critical issues related to analytical variables have challenged its reproducibility and accuracy. This study aimed to assess the analytical reliability of the OGTT for the diagnosis of GDM. A total of 1015 pregnant women underwent a 2 h 75 g OGTT between 24 and 28 weeks of gestation. As recommended by National Academy of Clinical Biochemistry, we considered the total maximum allowable error for glucose plasma measurement as <6.9%. Assuming the possibility of analytical errors within this range for each OGTT glucose plasma value, different scenarios of GDM occurrence were estimated. GDM prevalence with standard criteria was 12.2%, and no hypothetical scenarios have shown a comparable GDM prevalence. Considering all the three OGTT values estimated at the lowest or the highest allowed value according to total maximum allowable error, GDM prevalence significantly varied (4.5% and 25.3%, respectively). Our results indicate that the OGTT is not completely accurate for GDM diagnosis.
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