Evidence map›Paper›PMID 35160005›Full record

ArticleJournal of clinical medicine2022

Procalcitonin Predicts Bacterial Infection, but Not Long-Term Occurrence of Adverse Events in Patients with Acute Coronary Syndrome.

Rita Pavasini, Gioele Fabbri, Federico Marchini, Nicola Bianchi, Maria Angela Deserio, Federico Sanguettoli, Filippo Maria Verardi, Daniela Segala, Graziella Pompei, Elisabetta Tonet and 5 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Risk of Acute Myocardial Infarction Among Patients With Laboratory-Confirmed Invasive Pneumococcal Disease: A Self-Controlled Case Series Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Rita PavasiniUO Cardiologia, Azienda Ospedaliero Universitaria di Ferrara, 44124 Ferrara, Italy.ORCID 0000-0002-1763-9711
Gioele FabbriUO Cardiologia, Azienda Ospedaliero Universitaria di Ferrara, 44124 Ferrara, Italy.
Federico MarchiniUO Cardiologia, Azienda Ospedaliero Universitaria di Ferrara, 44124 Ferrara, Italy.ORCID 0000-0003-2622-4881
Nicola BianchiUO Cardiologia, Azienda Ospedaliero Universitaria di Ferrara, 44124 Ferrara, Italy.ORCID 0000-0002-4643-1629
Maria Angela DeserioUO Cardiologia, Azienda Ospedaliero Universitaria di Ferrara, 44124 Ferrara, Italy.
Federico SanguettoliUO Cardiologia, Azienda Ospedaliero Universitaria di Ferrara, 44124 Ferrara, Italy.
Filippo Maria VerardiUO Cardiologia, Azienda Ospedaliero Universitaria di Ferrara, 44124 Ferrara, Italy.ORCID 0000-0002-0760-6609
Daniela SegalaUO Malattie Infettive, Azienda Ospedaliero Universitaria di Ferrara, 44124 Ferrara, Italy.
Graziella PompeiUO Cardiologia, Azienda Ospedaliero Universitaria di Ferrara, 44124 Ferrara, Italy.ORCID 0000-0003-1901-0703
Elisabetta TonetUO Cardiologia, Azienda Ospedaliero Universitaria di Ferrara, 44124 Ferrara, Italy.
Matteo SerenelliUO Cardiologia, Azienda Ospedaliero Universitaria di Ferrara, 44124 Ferrara, Italy.
Serena CaglioniUO Cardiologia, Azienda Ospedaliero Universitaria di Ferrara, 44124 Ferrara, Italy.ORCID 0000-0001-8222-9236
Gabriele GuardigliUO Cardiologia, Azienda Ospedaliero Universitaria di Ferrara, 44124 Ferrara, Italy.ORCID 0000-0001-8300-3116
Gianluca CampoUO Cardiologia, Azienda Ospedaliero Universitaria di Ferrara, 44124 Ferrara, Italy.ORCID 0000-0002-5150-188X
Rosario CultreraUO Malattie Infettive, Azienda Ospedaliero Universitaria di Ferrara, 44124 Ferrara, Italy.
Arcispedale Sant'Anna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study compiles data to determine if procalcitonin (PCT) values may predict both the risk of bacterial infection and potentially negative long-term outcomes in patients with acute coronary syndromes (ACS). All patients with a diagnosis of ACS that had PCT levels assessed during the first 24 h of hospitalization were enrolled in this study. The primary outcome was to detect the presence of bacterial infection defined as the occurrence of fever and at least one positive blood or urinary culture with clinical signs of infection. The secondary outcome was to monitor the occurrence after 1 year of the composite outcome of all-cause mortality, stroke and myocardial infarction. Overall, 569 patients were enrolled (mean age 69.37 ± 14 years, 30% females). Of these, 44 (8%) met the criteria for bacterial infection. After multivariate analysis, PCT and SBP were found to be independent predictors of bacterial infections (OR for PCT above the cut-off 2.67, 95% CI 1.09-6.53,

Indexed as

acute coronary syndromeinfectionmortalitymyocardial infarctionprocalcitonin

Identifiers

PMID35160005
PMCPMC8836946
OpenAlexW4206946267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.