Evidence map›Paper›PMID 35159994›Full record

ArticleJournal of clinical medicine2022

Body Mass Index Specifiers in Anorexia Nervosa: Anything below the "Extreme"?

Federica Toppino, Paola Longo, Matteo Martini, Giovanni Abbate-Daga, Enrica Marzola

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Observational
  4. Parental and Peer Relationships and Their Impact on Symptom Severity in Adolescent Patients With Anorexia Nervosa.European eating disorders review : the journal of the Eating Disorders Association · 2026
    Article
  5. Article
  6. Severity levels of anorexia nervosa and atypical anorexia nervosa in a Korean cohort.European eating disorders review : the journal of the Eating Disorders Association · 2025
    Article
  7. Data mining identifies meaningful severity specifiers for anorexia nervosa.Journal of psychopathology and clinical science · 2025
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Federica ToppinoEating Disorders Center, Department of Neuroscience "Rita Levi Montalcini", "Città della Salute e della Scienza" Hospital of Turin, University of Turin, 10126 Turin, Italy.
Paola LongoEating Disorders Center, Department of Neuroscience "Rita Levi Montalcini", "Città della Salute e della Scienza" Hospital of Turin, University of Turin, 10126 Turin, Italy.ORCID 0000-0003-1347-7054
Matteo MartiniEating Disorders Center, Department of Neuroscience "Rita Levi Montalcini", "Città della Salute e della Scienza" Hospital of Turin, University of Turin, 10126 Turin, Italy.ORCID 0000-0001-8877-0138
Giovanni Abbate-DagaEating Disorders Center, Department of Neuroscience "Rita Levi Montalcini", "Città della Salute e della Scienza" Hospital of Turin, University of Turin, 10126 Turin, Italy.ORCID 0000-0002-5826-5664
Enrica MarzolaEating Disorders Center, Department of Neuroscience "Rita Levi Montalcini", "Città della Salute e della Scienza" Hospital of Turin, University of Turin, 10126 Turin, Italy.ORCID 0000-0003-1328-9678
University of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The validity of body mass index (BMI) specifiers for anorexia nervosa (AN) has been questioned, but their applicability to inpatients with extremely low BMIs and their prognostic validity are currently unknown. Therefore, we designed this study: (a) to test current BMI specifiers in severe inpatients; (b) to explore a "very extreme" specifier (VE-AN; BMI ≤ 13.5); and (c) to verify inpatients' hospitalization outcome according to BMI severity. We enrolled 168 inpatients with AN completing the following: Eating disorder Examination-Questionnaire, Eating Disorder Inventory-2, State-Trait Anxiety Inventory, Beck Depression Inventory, Body Shape Questionnaire, and EQ-5D-VAS. According to the current BMI classification, those with a BMI < 15 versus those with non-extreme AN (NE-AN, BMI ≥ 15) differed on all measures but the quality of life with those with NE-AN reporting more impaired scores on all measures. Adopting an exploratory classification comparing VE-AN, extreme AN (E-AN, BMI = 13.6-14.99), and NE-AN, no differences emerged between VE-AN and E-AN, while those with NE-AN reported significantly more impaired scores on all variables while the quality of life again did not differ across groups. Hospitalization outcome improved for all groups, independently of BMI. Groups differed concerning the length of stay that mirrored BMI severity and impacted also hospitalization outcomes. Taken together, our data support the lack of validity of current BMI specifiers in AN, even in the acute setting. Moreover, the exploratory subgroup of patients with BMI ≤ 13.5 did not delineate a clinically different group.

Indexed as

anxietybody imagedepressioneating disordershospitalizationoutcome

Identifiers

PMID35159994
PMCPMC8837073
OpenAlexW4207074742

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.