Evidence map›Paper›PMID 35159945›Full record

ArticleJournal of clinical medicine2022

Diminished Endothelial Function but Normal Vascular Structure in Adults with Tetralogy of Fallot.

Daniel Goeder, Renate Oberhoffer-Fritz, Leon Brudy, Laura Willinger, Michael Meyer, Peter Ewert, Jan Müller

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Daniel GoederGerman Heart Centre Munich, Department of Paediatric Cardiology and Congenital Heart Disease, Technical University Munich, 80636 Munich, Germany.
Renate Oberhoffer-FritzGerman Heart Centre Munich, Department of Paediatric Cardiology and Congenital Heart Disease, Technical University Munich, 80636 Munich, Germany.ORCID 0000-0002-3166-0488
Leon BrudyGerman Heart Centre Munich, Department of Paediatric Cardiology and Congenital Heart Disease, Technical University Munich, 80636 Munich, Germany.
Laura WillingerGerman Heart Centre Munich, Department of Paediatric Cardiology and Congenital Heart Disease, Technical University Munich, 80636 Munich, Germany.ORCID 0000-0002-8577-4480
Michael MeyerGerman Heart Centre Munich, Department of Paediatric Cardiology and Congenital Heart Disease, Technical University Munich, 80636 Munich, Germany.ORCID 0000-0003-3970-514X
Peter EwertGerman Heart Centre Munich, Department of Paediatric Cardiology and Congenital Heart Disease, Technical University Munich, 80636 Munich, Germany.ORCID 0000-0003-0253-1190
Jan MüllerGerman Heart Centre Munich, Department of Paediatric Cardiology and Congenital Heart Disease, Technical University Munich, 80636 Munich, Germany.ORCID 0000-0002-7530-2025

Funding

Kinderherzen Fördergemeinschaft Deutsche Kinderherzzentren e.V W-M-025/2017
6 · The paper itself

Abstract

The life expectancy of patients with Tetralogy of Fallot (ToF) has increased in recent years. As a result, other risk factors with later onset in life are in the focus of patient care. Endothelial function is an early indicator of cardiovascular risk and was investigated along further structural vessel properties. A total of 17 patients (41.7 ± 7.1 years, 8 women) with Tetralogy of Fallot were 1:2 matched for sex with 34 (38.9 ± 8.1 years, 16 women) healthy volunteers. Participants received an assessment of their endothelial function and a structural assessment of the aorta. Patients with ToF showed a reduced endothelial function determined by reactive hyperaemia index after adjusting for age, weight and height (ToF: 1.55 ± 0.31 vs. controls: 1.84 ± 0.47;

Indexed as

carotid intima-media thicknessEndoPATendothelium

Identifiers

PMID35159945
PMCPMC8836741

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.