Evidence map›Paper›PMID 35159921›Full record

ReviewNanomaterials (Basel, Switzerland)2022

Exploring Various Techniques for the Chemical and Biological Synthesis of Polymeric Nanoparticles.

Thiruchelvi Pulingam, Parisa Foroozandeh, Jo-Ann Chuah, Kumar Sudesh

Abstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed.

  1. Review
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  15. Unlocking the Potential ofPharmaceutics · 2025
    Review
  16. Article
  17. Review
  18. Polymeric Nanoparticles for Wound Healing.Pharmaceutical nanotechnology · 2025
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thiruchelvi PulingamEcobiomaterial Research Laboratory, School of Biological Sciences, Universiti Sains Malaysia, Gelugor 11800, Penang, Malaysia.
Parisa ForoozandehEcobiomaterial Research Laboratory, School of Biological Sciences, Universiti Sains Malaysia, Gelugor 11800, Penang, Malaysia.
Jo-Ann ChuahEcobiomaterial Research Laboratory, School of Biological Sciences, Universiti Sains Malaysia, Gelugor 11800, Penang, Malaysia.
Kumar SudeshEcobiomaterial Research Laboratory, School of Biological Sciences, Universiti Sains Malaysia, Gelugor 11800, Penang, Malaysia.ORCID 0000-0003-4756-9192

Funding

Ministry of Education Malaysia 203/PBIOLOGI/67811001
6 · The paper itself

Abstract

Nanoparticles (NPs) have remarkable properties for delivering therapeutic drugs to the body's targeted cells. NPs have shown to be significantly more efficient as drug delivery carriers than micron-sized particles, which are quickly eliminated by the immune system. Biopolymer-based polymeric nanoparticles (PNPs) are colloidal systems composed of either natural or synthetic polymers and can be synthesized by the direct polymerization of monomers (e.g., emulsion polymerization, surfactant-free emulsion polymerization, mini-emulsion polymerization, micro-emulsion polymerization, and microbial polymerization) or by the dispersion of preformed polymers (e.g., nanoprecipitation, emulsification solvent evaporation, emulsification solvent diffusion, and salting-out). The desired characteristics of NPs and their target applications are determining factors in the choice of method used for their production. This review article aims to shed light on the different methods employed for the production of PNPs and to discuss the effect of experimental parameters on the physicochemical properties of PNPs. Thus, this review highlights specific properties of PNPs that can be tailored to be employed as drug carriers, especially in hospitals for point-of-care diagnostics for targeted therapies.

Indexed as

emulsification solvent diffusionemulsification solvent evaporationnanoprecipitationnatural nanoparticlespolyhydroxyalkanoates (PHA)polymeric nanoparticles

Identifiers

PMID35159921
PMCPMC8839423

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.