Evidence map›Paper›PMID 35159842›Full record

ArticleNanomaterials (Basel, Switzerland)2022

Cancer Cytotoxicity of a Hybrid Hyaluronan-Superparamagnetic Iron Oxide Nanoparticle Material: An In-Vitro Evaluation.

Yen-Lan Chang, Pei-Bang Liao, Ping-Han Wu, Wei-Jen Chang, Sheng-Yang Lee, Haw-Ming Huang

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Nanotherapy of Glioblastoma-Where Hope Grows.International journal of molecular sciences · 2025
    Review
  3. Article
  4. Article
  5. An Overview of Antitumour Activity of Polysaccharides.Molecules (Basel, Switzerland) · 2022
    Review
  6. Toxicologic Concerns with Current Medical Nanoparticles.International journal of molecular sciences · 2022
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Yen-Lan ChangDivison of Prosthodontics, Department of Stomatology, Mackay Memorial Hospital, Taipei 10449, Taiwan.
Pei-Bang LiaoDepartment of Dentistry, Taipei Medical University Hospital, Taipei 11031, Taiwan.
Ping-Han WuGraduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei 11031, Taiwan.
Wei-Jen ChangSchool of Dentistry, Taipei Medical University, Taipei 11031, Taiwan.
Sheng-Yang LeeSchool of Dentistry, Taipei Medical University, Taipei 11031, Taiwan.
Haw-Ming HuangSchool of Dentistry, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0003-4184-3744
Taipei Medical University · TWMackay Memorial Hospital · TWTaipei Medical University Hospital · TWWan Fang Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While hyaluronic acid encapsulating superparamagnetic iron oxide nanoparticles have been reported to exhibit selective cytotoxicity toward cancer cells, it is unclear whether low-molecular-weight hyaluronic acid-conjugated superparamagnetic iron oxide nanoparticles also display such cytotoxicity. In this study, high-molecular-weight hyaluronic acid was irradiated with γ-ray, while Fe

Indexed as

cancerhyaluronansuperparamagnetic iron oxide nanoparticleTOF-SIM

Identifiers

PMID35159842
PMCPMC8839197
OpenAlexW4210331669

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.