Evidence map›Paper›PMID 35159772›Full record

ArticleNanomaterials (Basel, Switzerland)2022

Multimodal Contrast Agent Enabling pH Sensing Based on Organically Functionalized Gold Nanoshells with Mn-Zn Ferrite Cores.

Duong Thuy Bui, Radim Havelek, Karel Královec, Lenka Kubíčková, Jarmila Kuličková, Petr Matouš, Vít Herynek, Jaroslav Kupčík, Darina Muthná, Pavel Řezanka and 1 more

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Duong Thuy BuiInstitute of Physics, Czech Academy of Sciences, Cukrovarnická 10, 162 00 Prague, Czech Republic.ORCID 0000-0002-2014-3936
Radim HavelekDepartment of Medical Biochemistry, Faculty of Medicine in Hradec Králové, Charles University, Šimkova 870, 500 03 Hradec Králové, Czech Republic.ORCID 0000-0003-0528-1334
Karel KrálovecDepartment of Medical Biochemistry, Faculty of Medicine in Hradec Králové, Charles University, Šimkova 870, 500 03 Hradec Králové, Czech Republic.ORCID 0000-0001-9283-0930
Lenka KubíčkováInstitute of Physics, Czech Academy of Sciences, Cukrovarnická 10, 162 00 Prague, Czech Republic.
Jarmila KuličkováInstitute of Physics, Czech Academy of Sciences, Cukrovarnická 10, 162 00 Prague, Czech Republic.ORCID 0000-0003-4499-4142
Petr MatoušCenter for Advanced Preclinical Imaging (CAPI), First Faculty of Medicine, Charles University, Salmovská 2, 120 00 Prague, Czech Republic.
Vít HerynekCenter for Advanced Preclinical Imaging (CAPI), First Faculty of Medicine, Charles University, Salmovská 2, 120 00 Prague, Czech Republic.ORCID 0000-0002-1775-2394
Jaroslav KupčíkInstitute of Physics, Czech Academy of Sciences, Cukrovarnická 10, 162 00 Prague, Czech Republic.
Darina MuthnáDepartment of Medical Biochemistry, Faculty of Medicine in Hradec Králové, Charles University, Šimkova 870, 500 03 Hradec Králové, Czech Republic.
Pavel ŘezankaDepartment of Analytical Chemistry, University of Chemistry and Technology, Technická 5, 166 28 Prague, Czech Republic.ORCID 0000-0002-2997-9748
Ondřej KamanInstitute of Physics, Czech Academy of Sciences, Cukrovarnická 10, 162 00 Prague, Czech Republic.

Funding

Czech Science Foundation 18-13323SMinistry of Education Youth and Sports CZ.02.01./0.0./0.0./16_013/0001775Ministry of Education Youth and Sports CZ.02.1.01/0.0/0.0/16_019/0000760Ministry of Education Youth and Sports LM2015062Ministry of Education Youth and Sports LM2018096Ministry of Education Youth and Sports LM2018110Ministry of Education Youth and Sports LM2018129
6 · The paper itself

Abstract

Highly complex nanoparticles combining multimodal imaging with the sensing of physical properties in biological systems can considerably enhance biomedical research, but reports demonstrating the performance of a single nanosized probe in several imaging modalities and its sensing potential at the same time are rather scarce. Gold nanoshells with magnetic cores and complex organic functionalization may offer an efficient multimodal platform for magnetic resonance imaging (MRI), photoacoustic imaging (PAI), and fluorescence techniques combined with pH sensing by means of surface-enhanced Raman spectroscopy (SERS). In the present study, the synthesis of gold nanoshells with Mn-Zn ferrite cores is described, and their structure, composition, and fundamental properties are analyzed by powder X-ray diffraction, X-ray fluorescence spectroscopy, transmission electron microscopy, magnetic measurements, and UV-Vis spectroscopy. The gold surface is functionalized with four different model molecules, namely thioglycerol,

Indexed as

cell viabilitygold nanoshellsmagnetic nanoparticlesphotoacoustic imagingsurface-enhanced Raman spectroscopytransverse relaxivity

Identifiers

PMID35159772
PMCPMC8839728

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.