Evidence map›Paper›PMID 35159459›Full record

ArticleFoods (Basel, Switzerland)2022

Encapsulation of Pomegranate Peel Extract (

Leyla Sanhueza, Paula García, Begoña Giménez, José Manuel Benito, María Matos, Gemma Gutiérrez

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. FeACS omega · 2025
    Article
  8. Encapsulation of Indicaxanthin-RichFoods (Basel, Switzerland) · 2024
    Article
  9. Review
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Leyla SanhuezaDepartamento de Ciencia de los Alimentos y Tecnología Química, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Santiago 8380000, Chile.
Paula GarcíaDepartamento de Nutrición, Facultad de Medicina, Universidad de Chile, Santiago 8380453, Chile.
Begoña GiménezDepartamento de Ciencia y Tecnología de los Alimentos, Facultad Tecnológica, Universidad de Santiago de Chile, Santiago 9170124, Chile.
José Manuel BenitoDepartment of Biotechnology and Food Science, University of Burgos, Plaza Misael Bañuelos s/n, 09001 Burgos, Spain.ORCID 0000-0001-8899-0448
María MatosDepartment of Chemical and Environmental Engineering, Institute of Biotechnology of Asturias, University of Oviedo, 33006 Oviedo, Spain.ORCID 0000-0002-6980-0554
Gemma GutiérrezDepartment of Chemical and Environmental Engineering, Institute of Biotechnology of Asturias, University of Oviedo, 33006 Oviedo, Spain.ORCID 0000-0003-2700-4944
Universidad de Oviedo · ESUniversity of Chile · CLUniversidad de Burgos · ESUniversidad de Santiago de Chile · CL

Funding

Gobierno del Principado de Asturias IDI/2018/000185Ministry of Economy, Industry and Competitiveness PID2019-105311RB-I00University of Chile 11160541
6 · The paper itself

Abstract

Pomegranate peel is an agro-industrial waste that can be used as source of punicalagin, a polyphenolic compound with several beneficial effects on health. Since, once extracted, punicalagin is prone to degradation, its encapsulation by double emulsions can be an alternative to protect the active compound and control its release. The aim of this investigation was to evaluate the feasibility of encapsulating pomegranate peel extract (PPE) in double emulsions using different types of oils (castor, soybean, sunflower, Miglyol and orange) in a ratio of 70:30 (oil:PPE) and emulsification methods (direct membrane emulsification and mechanical agitation), using polyglycerol polyricinoleate (PGPR) and Tween 80 as lipophilic and hydrophilic emulsifiers, respectively. Direct membrane emulsification (DME) led to more stable emulsions during storage. Droplet size, span values, morphology and encapsulation efficiency (EE) were better for double emulsions (DEs) prepared by DME than for mechanical agitation (MA). DEs formulated using Miglyol or sunflower oil as the oily phase could be considered as suitable food grade systems to encapsulate punicalagin with concentrations up to 11,000 mg/L of PPE.

Indexed as

double emulsion formulationemulsion stabilitymembrane emulsificationoil viscositypunicalagin encapsulation

Identifiers

PMID35159459
PMCPMC8833941
OpenAlexW4210606613

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.