Evidence map›Paper›PMID 35159328›Full record

ArticleCells2022

Lifespan Increase of

Lea Schürmanns, Andrea Hamann, Heinz D Osiewacz

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Anti-Aging Potential of Avocado Oil via Its Antioxidant Effects.Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  4. Review
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Lea SchürmannsFaculty of Biosciences, Institute for Molecular Biosciences, Goethe University, Max-von-Laue-Street 9, 60438 Frankfurt, Germany.ORCID 0000-0001-7428-6548
Andrea HamannFaculty of Biosciences, Institute for Molecular Biosciences, Goethe University, Max-von-Laue-Street 9, 60438 Frankfurt, Germany.ORCID 0000-0001-9821-7491
Heinz D OsiewaczFaculty of Biosciences, Institute for Molecular Biosciences, Goethe University, Max-von-Laue-Street 9, 60438 Frankfurt, Germany.ORCID 0000-0002-0360-6994
Goethe University Frankfurt · DE

Funding

Deutsche Forschungsgemeinschaft 25913077-SFB1177
6 · The paper itself

Abstract

The maintenance of cellular homeostasis over time is essential to avoid the degeneration of biological systems leading to aging and disease. Several interconnected pathways are active in this kind of quality control. One of them is autophagy, the vacuolar degradation of cellular components. The absence of the sorting nexin PaATG24 (SNX4 in other organisms) has been demonstrated to result in impairments in different types of autophagy and lead to a shortened lifespan. In addition, the growth rate and the size of vacuoles are strongly reduced. Here, we report how an oleic acid diet leads to longevity of the wild type and a

Indexed as

PodosporaAutophagyEnergy MetabolismHumansLongevityMitochondriaOleic AcidOleic AcidagingATG24autophagyERmembrane traffickingmitochondriaperoxisomesPodospora anserina

Identifiers

PMID35159328
PMCPMC8834509
OpenAlexW4210272986

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.