Trial reportCells2022
Energy Drinks and Their Acute Effects on Heart Rhythm and Electrocardiographic Time Intervals in Healthy Children and Teenagers: A Randomized Trial.
Trial report in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Effects of Energy Drinks on the Cardiovascular System: A Systematic Review.Current cardiology reports · 2025Pooled it
- Impact of Acute Energy Drink Consumption on Heart Rate Variability in Children and Adolescents. A Randomized Trial.Pediatric cardiology · 2026Trial
- Energy drinks: effects on pediatric 24-h ambulatory blood pressure monitoring. A randomized trial.Pediatric research · 2023Trial
- Energy Drinks Decrease Left Ventricular Efficiency in Healthy Children and Teenagers: A Randomized Trial.Sensors (Basel, Switzerland) · 2022Trial
- Trial
- Energy Drinks and Arrhythmias in Adolescents and Young Adults: A Narrative Review of the Last Decade.Medicina (Kaunas, Lithuania) · 2026Review
- The effects of energy drink consumption in children and adolescents: a cross-sectional study and the recommendations of the Italian Pediatric Society.Italian journal of pediatrics · 2026Article
- Caffeine and the Young Heart: A Systematic Review of Arrhythmogenic Risks in Children and Adolescents.Pediatric cardiology · 2026Review
- Acid-Induced Surface Degradation of Metallic Biomaterials: Alloy-Dependent Behavior and Implications for Surface Functionality.Journal of functional biomaterials · 2026Article
- Review
- Chronic high consumption of energy drinks and cardiovascular risk in adolescents-results of the EDKAR-study.European journal of epidemiology · 2025Article
- Energy Drink Exposures and Trends in Children and Young Adults Reported to the National Poison Data System.Progress in pediatric cardiology · 2025Article
- Patterns of Energy Drink Use, Risk Perception, and Regulatory Attitudes in the Adult Polish Population: Results of a Cross-Sectional Survey.Nutrients · 2025Article
- Emerging cardiovascular risk factors in childhood and adolescence: a narrative review.European journal of pediatrics · 2025Review
- Influence of energy drink consumption on perceived quality of life in young adults and adult population.Frontiers in nutrition · 2025Article
- Acute Cardiovascular Effects of Simultaneous Energy Drink and Alcohol Consumption in Young Adults: A Review of Case Reports.Pediatric reports · 2024Review
- Article
- Energy Drink Consumption Among Physically Active Polish Adolescents: Gender and Age-Specific Public Health Issue.International journal of public health · 2024Article
- Energy Drinks and Adverse Health Events in Children and Adolescents: A Literature Review.Nutrients · 2023Review
- Energy Drinks and Their Acute Effects on Arterial Stiffness in Healthy Children and Teenagers: A Randomized Trial.Journal of clinical medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Beyond their effect on blood pressure, the effect of energy drinks on heart rate in children and teenagers has not been evaluated until now. Thus, this study aimed to investigate the acute cardiovascular effects of energy drinks in healthy children and teenagers. Twenty-six children and adolescents (mean age 14.49 years) received a commercially available energy drink (ED) and placebo on two consecutive days based on the maximum caffeine dosage as proposed by the European Food Safety Authority. Heart rhythm and electrocardiographic time intervals were assessed in a prospective, randomized, double-blind, placebo-controlled, crossover clinical study design. ED consumption resulted in a significantly increased number of supraventricular extrasystoles (SVES) compared to the placebo, whereas supraventricular tachycardia or malignant ventricular arrhythmias were not observed. The mean heart rate (HR) was significantly lower following consumption of EDs. In contrast, QTc intervals were not affected by EDs. Being the first of its kind, this trial demonstrates the cardiovascular and rhythmological effects of EDs in minors. Interestingly, EDs were associated with adverse effects on heart rhythm. Whether higher dosages or consumption in children with preexisting conditions may cause potentially harmful disorders was beyond the scope of this pilot study and remains to be determined in future trials. Trial Registration Number (DRKS-ID): DRKS00027580.
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