Evidence map›Paper›PMID 35159293›Full record

ArticleCells2022

Secreted Neutrophil Gelatinase-Associated Lipocalin Shows Stronger Ability to Inhibit Cyst Enlargement of ADPKD Cells Compared with Nonsecreted Form.

Hsin-Yin Chuang, Wen-Yih Jeng, Ellian Wang, Si-Tse Jiang, Chen-Ming Hsu, Hsiu Mei Hsieh-Li, Yuan-Yow Chiou

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Hsin-Yin ChuangDepartment of Life Science, National Taiwan Normal University, Taipei 11677, Taiwan.ORCID 0000-0003-3615-600X
Wen-Yih JengUniversity Center for Bioscience and Biotechnology, National Cheng Kung University, Tainan 70101, Taiwan.ORCID 0000-0001-5870-587X
Ellian WangDivision of Pediatric Nephrology, Department of Pediatrics, National Cheng Kung University Hospital, Tainan 70403, Taiwan.
Si-Tse JiangInstitute of Clinical Medicine, Medical College, National Cheng Kung University, Tainan 70101, Taiwan.ORCID 0000-0002-5145-258X
Chen-Ming HsuDepartment of Life Science, National Taiwan Normal University, Taipei 11677, Taiwan.
Hsiu Mei Hsieh-LiDepartment of Life Science, National Taiwan Normal University, Taipei 11677, Taiwan.
Yuan-Yow ChiouDivision of Pediatric Nephrology, Department of Pediatrics, National Cheng Kung University Hospital, Tainan 70403, Taiwan.ORCID 0000-0002-5279-0660
National Taiwan Normal University · TWNational Cheng Kung University Hospital · TWNational Cheng Kung University · TWNational Institutes of Applied Research · TW

Funding

Ministry of Science and Technology (Taiwan) 107-2622-B-006-005-CC2Ministry of Science and Technology (Taiwan) 108-2622-B-006-002-CC2
6 · The paper itself

Abstract

Polycystic kidney disease (PKD) is one of the most common inherited diseases and is characterized by the development of fluid-filled cysts along multiple segments of the nephron. Autosomal dominant polycystic kidney disease (ADPKD) is the most common form of PKD, which is caused by mutations in either

Indexed as

CystsLipocalin-2Polycystic Kidney, Autosomal DominantAnimalsMiceTRPP Cation ChannelsLcn2 protein, mouseLipocalin-2TRPP Cation Channels3D cultureADPKDneutrophil gelatinase-associated lipocalin

Identifiers

PMID35159293
PMCPMC8834617
OpenAlexW4210577685

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.