Evidence map›Paper›PMID 35159289›Full record

ReviewCells2022

A Comprehensive Review on the Surgical Aspect of Lung Transplant Models in Mice and Rats.

Xin Jin, Janne Kaes, Jan Van Slambrouck, Ilhan Inci, Stephan Arni, Vincent Geudens, Tobias Heigl, Yanina Jansen, Marianne S Carlon, Robin Vos and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Blood vessels as primary site of rejection in murine lung transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  4. Donor-Specific Blood Transfusion Induces a Transfusion-Related Early Protective Effect in Murine Lung Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Donor-Specific Blood Transfusion in Lung Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Review
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 3 countries.

Xin JinLaboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Department CHROMETA, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-3295-7179
Janne KaesLaboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Department CHROMETA, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-3326-3769
Jan Van SlambrouckLaboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Department CHROMETA, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-7069-1535
Ilhan InciDepartment of Thoracic Surgery, University Hospital Zürich, 8091 Zürich, Switzerland.ORCID 0000-0003-3937-7705
Stephan ArniDepartment of Thoracic Surgery, University Hospital Zürich, 8091 Zürich, Switzerland.ORCID 0000-0001-5497-8256
Vincent GeudensLaboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Department CHROMETA, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-4386-1746
Tobias HeiglLaboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Department CHROMETA, KU Leuven, 3000 Leuven, Belgium.
Yanina JansenLaboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Department CHROMETA, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-8322-9841
Marianne S CarlonLaboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Department CHROMETA, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-8263-0350
Robin VosLaboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Department CHROMETA, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-3468-9251
Dirk Van RaemdonckLaboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Department CHROMETA, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0003-1261-0992
Yi ZhangDepartment of Thoracic Surgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
Bart M VanaudenaerdeLaboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Department CHROMETA, KU Leuven, 3000 Leuven, Belgium.
Laurens J CeulemansLaboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Department CHROMETA, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-4261-7100
KU Leuven · BEUniversity Hospital of Zurich · CHCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung transplantation improves the outcome and quality of life of patients with end-stage pulmonary disease. However, the procedure is still hampered by the lack of suitable donors, the complexity of the surgery, and the risk of developing chronic lung allograft dysfunction. Over the past decades, translational experiments in animal models have led to a better understanding of physiology and immunopathology following the lung transplant procedure. Small animal models (e.g., rats and mice) are mostly used in experiments regarding immunology and pathobiology and are preferred over large animal models due to the ethical aspects, the cost-benefit balance, and the high throughput possibility. In this comprehensive review, we summarize the reported surgical techniques for lung transplantation in rodent models and the management of perioperative complications. Furthermore, we propose a guide to help identify the appropriate species for a given experiment and discuss recent experimental findings in small animal lung transplant models.

Indexed as

Lung TransplantationQuality of LifeAnimalsHumansLungMiceRatsRodentiaTissue Donorslung transplantationmicrosurgerymouseratrodentsmall animal model

Identifiers

PMID35159289
PMCPMC8833959
OpenAlexW4210710583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.