Evidence map›Paper›PMID 35159249›Full record

ArticleCells2022

A Distinct

Manoj Kumar Mishra, Jianxiong Wang, Reza Mirzaei, Rigel Chan, Helvira Melo, Ping Zhang, Chang-Chun Ling, Aldo Bruccoleri, Lin Tang, V Wee Yong

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Manoj Kumar MishraHotchkiss Brain Institute, Department of Clinical Neurosciences, University of Calgary, Calgary, AB T2N 4N1, Canada.
Jianxiong WangHotchkiss Brain Institute, Department of Clinical Neurosciences, University of Calgary, Calgary, AB T2N 4N1, Canada.
Reza MirzaeiHotchkiss Brain Institute, Department of Clinical Neurosciences, University of Calgary, Calgary, AB T2N 4N1, Canada.ORCID 0000-0002-2393-2770
Rigel ChanHotchkiss Brain Institute, Department of Clinical Neurosciences, University of Calgary, Calgary, AB T2N 4N1, Canada.
Helvira MeloHotchkiss Brain Institute, Department of Clinical Neurosciences, University of Calgary, Calgary, AB T2N 4N1, Canada.
Ping ZhangDepartment of Chemistry, University of Calgary, Calgary, AB T2N 4N1, Canada.
Chang-Chun LingDepartment of Chemistry, University of Calgary, Calgary, AB T2N 4N1, Canada.
Aldo BruccoleriAnthoBio, Calgary, AB T2N 4N1, Canada.ORCID 0000-0003-1139-866X
Lin TangAnthoBio, Calgary, AB T2N 4N1, Canada.
V Wee YongHotchkiss Brain Institute, Department of Clinical Neurosciences, University of Calgary, Calgary, AB T2N 4N1, Canada.ORCID 0000-0002-2600-3563
University of Calgary · CA

Funding

CIHR 2015
6 · The paper itself

Abstract

Iron deposition in the brain begins early in multiple sclerosis (MS) and continues unabated. Ferrous iron is toxic to neurons, yet the therapies used in MS do not counter iron neurotoxicity. Extracts of

Indexed as

HibiscusMultiple SclerosisNeurotoxicity SyndromesThioctic AcidAnimalsAntioxidantsIronMicePlant ExtractsAntioxidantsIronPlant ExtractsThioctic Acidexperimental autoimmune encephalomyelitishuman neuronsironmultiple sclerosisneurodegenerationneuroprotectionoxidative stress

Identifiers

PMID35159249
PMCPMC8834068
OpenAlexW4210448776

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.