Evidence map›Paper›PMID 35159243›Full record

ArticleCells2022

Mitochondria Fusion upon SERCA Inhibition Prevents Activation of the NLRP3 Inflammasome in Human Monocytes.

Ana Catarina Pereira, Nuno Madeira, Sofia Morais, António Macedo, Maria Teresa Cruz, Cláudia M F Pereira

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ana Catarina PereiraCNC-Center for Neuroscience and Cell Biology, CIBB-Center for Innovative Biomedicine and Biotechnology, University of Coimbra, Rua Larga-Faculdade de Medicina, 1°andar-Polo I Universidade de Coimbra, 3004-504 Coimbra, Portugal.ORCID 0000-0002-3269-0865
Nuno MadeiraFaculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.ORCID 0000-0001-5009-8841
Sofia MoraisFaculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.
António MacedoFaculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.ORCID 0000-0003-2180-2718
Maria Teresa CruzCNC-Center for Neuroscience and Cell Biology, CIBB-Center for Innovative Biomedicine and Biotechnology, University of Coimbra, Rua Larga-Faculdade de Medicina, 1°andar-Polo I Universidade de Coimbra, 3004-504 Coimbra, Portugal.ORCID 0000-0001-9846-6754
Cláudia M F PereiraCNC-Center for Neuroscience and Cell Biology, CIBB-Center for Innovative Biomedicine and Biotechnology, University of Coimbra, Rua Larga-Faculdade de Medicina, 1°andar-Polo I Universidade de Coimbra, 3004-504 Coimbra, Portugal.
Hospitais da Universidade de Coimbra · PTUniversity of Coimbra · PT

Funding

European Regional Development Fund (ERDF) CENTRO-01-0145-FEDER-000012Fundação para a Ciência e a Tecnologia POCI-01-0145-FEDER-028214 (MAM4BD) and POCI-01-0145-FEDER-029369 and UIDB/04539/2020 and UIDP/04539/2020Fundação para a Ciência e a Tecnologia SFRH/BD/148653/2019
6 · The paper itself

Abstract

Sarco/endoplasmic reticulum Ca

Indexed as

InflammasomesMitochondrial DynamicsNLR Family, Pyrin Domain-Containing 3 ProteinSarcoplasmic Reticulum Calcium-Transporting ATPasesHumansInflammationMitochondriaMonocytesThapsigarginInflammasomesNLR Family, Pyrin Domain-Containing 3 ProteinNLRP3 protein, humanSarcoplasmic Reticulum Calcium-Transporting ATPasesThapsigargincalcium homeostasisendoplasmic reticulum (ER) stressimmune systemmitochondria dynamicssterile inflammation

Identifiers

PMID35159243
PMCPMC8833979
OpenAlexW4210564278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.