Evidence map›Paper›PMID 35159208›Full record

ReviewCells2022

KRAS as a Modulator of the Inflammatory Tumor Microenvironment: Therapeutic Implications.

Flávia Pereira, Anabela Ferreira, Celso Albuquerque Reis, Maria João Sousa, Maria José Oliveira, Ana Preto

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Review
  7. KRASScience advances · 2026
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. KRAS Inhibitors in Pancreas Cancer: Facts and Hopes about the Immunotherapy We Have All Been Waiting for.Clinical cancer research : an official journal of the American Association for Cancer Research · 2026
    Review
  13. Article
  14. Molecular origin, discovery, validation and application of neoantigens.Asian journal of pharmaceutical sciences · 2026
    Review
  15. Review
  16. Review
  17. COPD-Lung Cancer Comorbidity: Mechanistic Insights and Precision Oncology Implications.International journal of chronic obstructive pulmonary disease · 2026
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Flávia PereiraCentre of Molecular and Environmental Biology (CBMA), Department of Biology, Campus de Gualtar, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0003-2608-6511
Anabela FerreiraCentre of Molecular and Environmental Biology (CBMA), Department of Biology, Campus de Gualtar, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0002-1417-3418
Celso Albuquerque ReisInstitute for Research and Innovation in Health (i3S), University of Porto, 4200-135 Porto, Portugal.ORCID 0000-0002-0286-6639
Maria João SousaCentre of Molecular and Environmental Biology (CBMA), Department of Biology, Campus de Gualtar, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0001-9424-4150
Maria José OliveiraInstitute for Research and Innovation in Health (i3S), University of Porto, 4200-135 Porto, Portugal.ORCID 0000-0002-0724-0272
Ana PretoCentre of Molecular and Environmental Biology (CBMA), Department of Biology, Campus de Gualtar, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0002-7302-0630
Universidade do Porto · PTUniversity of Minho · PT

Funding

Fundação para a Ciência e Tecnologia PTDC/QUIQIN/28662/2017Fundação para a Ciência e Tecnologia SFRH/BD/140137/2018Fundação para a Ciência e Tecnologia SFRH/BD/142486/2018Fundação para a Ciência e Tecnologia UIDB/4050/2020Fundação para a Ciência e Tecnologia UID/BIA/04050/2019
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Lung NeoplasmsProto-Oncogene Proteins p21(ras)HumansSignal TransductionTumor MicroenvironmentKRAS protein, humanProto-Oncogene Proteins p21(ras)colorectal cancerinflammationKRAS mutationslung cancerpancreatic cancertherapytumor microenvironment

Identifiers

PMID35159208
PMCPMC8833974
OpenAlexW4210550996

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.