Evidence map›Paper›PMID 35159141›Full record

ArticleCells2022

Metabolic Alterations in a

Cristina Solana-Manrique, Francisco José Sanz, Isabel Torregrosa, Martina Palomino-Schätzlein, Carolina Hernández-Oliver, Antonio Pineda-Lucena, Nuria Paricio

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Dopaminergic neuron metabolism: relevance for understanding Parkinson's disease.Metabolomics : Official journal of the Metabolomic Society · 2024
    Review
  5. Review
  6. Flight to insight: maximizing the potential ofFrontiers in molecular neuroscience · 2024
    Article
  7. A new metabolic model ofLife science alliance · 2023
    Article
  8. Article
  9. Review
  10. Article
  11. Exploring the link between Parkinson's disease and type 2 diabetes mellitus in Drosophila.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Cristina Solana-ManriqueDepartamento de Genética, Facultad CC Biológicas, Instituto Universitario de Biotecnología y Biomedicina (BIOTECMED), Universidad de Valencia, 46100 Burjassot, Spain.ORCID 0000-0001-5148-8796
Francisco José SanzDepartamento de Genética, Facultad CC Biológicas, Instituto Universitario de Biotecnología y Biomedicina (BIOTECMED), Universidad de Valencia, 46100 Burjassot, Spain.
Isabel TorregrosaDepartamento de Genética, Facultad CC Biológicas, Instituto Universitario de Biotecnología y Biomedicina (BIOTECMED), Universidad de Valencia, 46100 Burjassot, Spain.
Martina Palomino-SchätzleinCentro de Investigación Príncipe Felipe, 46012 Valencia, Spain.ORCID 0000-0001-7303-0743
Carolina Hernández-OliverInstituto de Investigación Sanitaria La Fe, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.
Antonio Pineda-LucenaInstituto de Investigación Sanitaria La Fe, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.ORCID 0000-0002-3532-8781
Nuria ParicioDepartamento de Genética, Facultad CC Biológicas, Instituto Universitario de Biotecnología y Biomedicina (BIOTECMED), Universidad de Valencia, 46100 Burjassot, Spain.ORCID 0000-0001-7193-2532
Universitat de València · ESInstituto de Investigación Sanitaria La Fe · ESCentro de Investigacion Principe Felipe · ES

Funding

University of Valencia 08-BIOPARK-PARICIO-PINEDA-2017-AUniversity of Valencia UV-INV-AE17-702300
6 · The paper itself

Abstract

Parkinson's disease (PD) is the second-most common neurodegenerative disorder, whose physiopathology is still unclear. Moreover, there is an urgent need to discover new biomarkers and therapeutic targets to facilitate its diagnosis and treatment. Previous studies performed in PD models and samples from PD patients already demonstrated that metabolic alterations are associated with this disease. In this context, the aim of this study is to provide a better understanding of metabolic disturbances underlying PD pathogenesis. To achieve this goal, we used a

Indexed as

Drosophila ProteinsParkinson DiseaseProtein Deglycase DJ-1AnimalsDisease Models, AnimalDrosophilaHumansNerve Tissue ProteinsOxidative StressDJ-1beta protein, DrosophilaDrosophila ProteinsNerve Tissue ProteinsProtein Deglycase DJ-1DJ-1DrosophilametabolomicsNMR spectroscopyParkinson’s disease

Identifiers

PMID35159141
PMCPMC8834223
OpenAlexW4205478630

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.