Evidence map›Paper›PMID 35159074›Full record

ArticleCancers2022

The Impact of an Incidental Dose on Axillary Tumor Control and Toxicity in Localized Breast Cancer: A Retrospective Analysis.

Martin Schmitt, Isabelle Chambrelant, Parigna Hong Chheang, Carole Pflumio, Carole Hild, Thierry Petit, Georges Noël

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Martin SchmittRadiotherapy Department, Strasbourg Europe Cancer Institute, 17 Rue Albert Calmette, 67200 Strasbourg, France.ORCID 0000-0002-3969-6610
Isabelle ChambrelantRadiotherapy Department, Strasbourg Europe Cancer Institute, 17 Rue Albert Calmette, 67200 Strasbourg, France.ORCID 0000-0002-8102-771X
Parigna Hong ChheangRadiotherapy Department, Khmer Soviet Friendship Hospital, Yuthapol Khemarak Phoumin Blvd, Phnom Penh 12306, Cambodia.
Carole PflumioMedical Oncology Department, Strasbourg Europe Cancer Institute, 17 Rue Albert Calmette, 67200 Strasbourg, France.
Carole HildBreast Surgery Department, Strasbourg Europe Cancer Institute, 17 Rue Albert Calmette, 67200 Strasbourg, France.
Thierry PetitMedical Oncology Department, Strasbourg Europe Cancer Institute, 17 Rue Albert Calmette, 67200 Strasbourg, France.
Georges NoëlRadiotherapy Department, Strasbourg Europe Cancer Institute, 17 Rue Albert Calmette, 67200 Strasbourg, France.ORCID 0000-0003-4952-5572
Institut de Cancérologie Strasbourg · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe dosimetric analysis of the incidental axillary dose delivered to axillary lymph node levels I-III by different techniques of whole breast irradiation and the analysis of prognostic factors of axillary recurrence of breast cancer.

methodsWe perform a retrospective analysis that includes 171 patients with localized breast carcinoma irradiated at Centre Paul Strauss. To be included in the study, patients had to have a histological confirmation of breast cancer diagnosis, surgical treatment without axillary lymph node dissection (ALND), whole breast irradiation without axillary irradiation by a specific field, and a treatment plan available.

resultsThree patients had lymph node recurrence. There was no significant correlation between the maximal or mean dose delivered at the three axillary levels and the risk of axillary lymph node recurrence. There was no significant correlation between the irradiation technique and the risk of axillary lymph node recurrence. Two patients, both in the HT group, had lymphoedema. There was significantly more lymphoedema in the HT group than in the ST and IMRT groups (

conclusionThe irradiation technique has an influence on the incidental dose delivered to the axillary area, but has no influence on the risk of axillary recurrence. The risk of lymphoedema could be related to the use of HT and the mean dose delivered at level II.

Indexed as

axillary lymph nodebreast carcinomadosimetric analysisintensity-modulated radiotherapyradiotherapythree-dimensional radiotherapy

Identifiers

PMID35159074
PMCPMC8834453
OpenAlexW4210814974

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.