Evidence map›Paper›PMID 35159031›Full record

ArticleCancers2022

BKV Related Hemorrhagic Cystitis-An Insight into Risk Factors and Later Complications-An Analysis on Behalf of Polish Adult Leukemia Group.

Jarosław Dybko, Agnieszka Piekarska, Siddarth Agrawal, Sebastian Makuch, Donata Urbaniak-Kujda, Monika Biernat, Blanka Rybka, Magdalena Dutka, Alicja Sadowska-Klasa, Sebastian Giebel and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Jarosław DybkoDepartment of Hematology and Cellular Transplantation, Lower Silesian Oncology Center, 53-413 Wroclaw, Poland.ORCID 0000-0003-3555-2887
Agnieszka PiekarskaDepartment of Hematology and Transplantology, Medical University of Gdansk, 80-214 Gdansk, Poland.ORCID 0000-0002-1593-8005
Siddarth AgrawalDepartment and Clinic of Internal Medicine, Occupational Diseases, Hypertension and Clinical Oncology, Wroclaw Medical University, 50-556 Wroclaw, Poland.ORCID 0000-0003-1118-5090
Sebastian MakuchDepartment of Clinical and Experimental Pathology, Wroclaw Medical University, 50-368 Wroclaw, Poland.
Donata Urbaniak-KujdaDepartment of Hematology and Bone Marrow Transplantation, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Monika BiernatDepartment of Hematology and Bone Marrow Transplantation, Wroclaw Medical University, 50-367 Wroclaw, Poland.ORCID 0000-0003-3161-3398
Blanka RybkaDepartment of Pediatric Bone Marrow Transplantation, Oncology, and Hematology, Wroclaw Medical University, 50-556 Wroclaw, Poland.
Magdalena DutkaDepartment of Hematology and Transplantology, Medical University of Gdansk, 80-214 Gdansk, Poland.ORCID 0000-0001-8112-3974
Alicja Sadowska-KlasaDepartment of Hematology and Transplantology, Medical University of Gdansk, 80-214 Gdansk, Poland.
Sebastian GiebelDepartment of Bone Marrow Transplantation and Hematology-Oncology, National Research Institute of Oncology, 44-102 Gliwice, Poland.
Lidia GilDepartment of Hematology and Bone Marrow Transplantation, Poznań University of Medical Sciences, 60-569 Poznan, Poland.
Wroclaw Medical University · PLGdańsk Medical University · PLLublin Oncology Center · PLPoznan University of Medical Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BK virus reactivation increases the likelihood of hemorrhagic cystitis (HC) after allogeneic hematopoietic stem cell transplant (HCT). In this study, we aimed to identify predictive and risk factors associated with the increased occurrence of this condition following HCT. On a group of 124 patients aged ≤71 years old (median 40 years) who underwent HCT, we analyzed sex, age, time from diagnosis to transplantation, type of conditioning, donor's relationship, age, and sex, the impact of immunosuppression with different drugs, and acute and chronic GVHD, BK viremia and viruria as potential factors increasing the risk of BK-related HC after HCT. HC occurred among 24 patients (24/124; 29.2%). A significant correlation was observed between HC incidences after HCT, BK viremia and viruria, and acute GVHD occurrence. Furthermore, the level of BKV DNA in serum at day +21 (>0.75 × 10

Indexed as

allogeneic hematopoietic stem cell transplantationBK virusrisk factorsviremia

Identifiers

PMID35159031
PMCPMC8833693
OpenAlexW4210698992

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.