Evidence map›Paper›PMID 35158913›Full record

ArticleCancers2022

Hematotoxicity and Nephrotoxicity in Prostate Cancer Patients Undergoing Radioligand Therapy with [

Philipp E Hartrampf, Franz-Xaver Weinzierl, Sebastian E Serfling, Martin G Pomper, Steven P Rowe, Takahiro Higuchi, Anna Katharina Seitz, Hubert Kübler, Andreas K Buck, Rudolf A Werner

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Quantitative PSMA PET Biomarkers for Predicting Response toJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Pooled it
  2. Could we reduce renal toxicity of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Hematological toxicity of [EJNMMI radiopharmacy and chemistry · 2025
    Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Early biochemical and radiographic response after one cycle of [European journal of nuclear medicine and molecular imaging · 2023
    Article
  12. SUVEuropean journal of nuclear medicine and molecular imaging · 2023
    Article
  13. Review
  14. Article
  15. Article
  16. Matched-pair analysis of [European journal of nuclear medicine and molecular imaging · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Philipp E HartrampfDepartment of Nuclear Medicine, University Hospital Wuerzburg, Oberdürrbacherstraße 6, 97080 Wurzburg, Germany.ORCID 0000-0001-5622-9849
Franz-Xaver WeinzierlDepartment of Nuclear Medicine, University Hospital Wuerzburg, Oberdürrbacherstraße 6, 97080 Wurzburg, Germany.
Sebastian E SerflingDepartment of Nuclear Medicine, University Hospital Wuerzburg, Oberdürrbacherstraße 6, 97080 Wurzburg, Germany.
Martin G PomperThe Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 601 N Caroline Str., Baltimore, MD 21205, USA.ORCID 0000-0001-6753-3010
Steven P RoweThe Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 601 N Caroline Str., Baltimore, MD 21205, USA.ORCID 0000-0003-2897-4694
Takahiro HiguchiDepartment of Nuclear Medicine, University Hospital Wuerzburg, Oberdürrbacherstraße 6, 97080 Wurzburg, Germany.
Anna Katharina SeitzDepartment of Urology and Paediatric Urology, University Hospital Wuerzburg, Oberdürrbacherstraße 6, 97080 Wurzburg, Germany.
Hubert KüblerDepartment of Urology and Paediatric Urology, University Hospital Wuerzburg, Oberdürrbacherstraße 6, 97080 Wurzburg, Germany.
Andreas K BuckDepartment of Nuclear Medicine, University Hospital Wuerzburg, Oberdürrbacherstraße 6, 97080 Wurzburg, Germany.
Rudolf A WernerDepartment of Nuclear Medicine, University Hospital Wuerzburg, Oberdürrbacherstraße 6, 97080 Wurzburg, Germany.
Universitätsklinikum Würzburg · DEJohns Hopkins University · USOkayama University · JP

Funding

Interdisziplinäres Zentrum für Klinische Forschung Würzburg Z-2/85
6 · The paper itself

Abstract

(1) Background: Prostate-specific membrane antigen (PSMA)-directed radioligand therapy (RLT) has shown remarkable results in patients with advanced prostate cancer. We aimed to evaluate the toxicity profile of the PSMA ligand [

Indexed as

177LuCTCAEhematotoxicitynephrotoxicityPSMAradioligand therapyRLT

Identifiers

PMID35158913
PMCPMC8833540
OpenAlexW4210435640

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.