ReviewCancers2022
Management of Early-Stage Cervical Cancer: A Literature Review.
Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Impact of adjuvant therapy after radical hysterectomy for early-stage cervical cancer on mortality and recurrence: a systematic review and meta-analysis.Frontiers in oncology · 2026Pooled it
- Using a social marketing approach to increase the pap-smear test uptake: randomized controlled trial among women residing in urban region.BMC women's health · 2025Trial
- Clinicopathological and Prognostic Significance of TROP2 and HER3 Expression in Early-Stage Cervical Carcinoma.Diagnostics (Basel, Switzerland) · 2026Article
- PIN1 enhances SUMOylation of YAP1 and inhibits ferroptosis via autophagy-dependent degradation of ACSL4 in cervical cancer.Cell death discovery · 2026Article
- Rural-Urban Differences in Cervical Cancer Screening Patterns: A Cross-Sectional Analysis of the 2021 National Health Interview Survey (NHIS).The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2026Article
- Preoperative prediction of cervical cancer recurrence using explainable MRI radiomics: a SHAP-Guided machine learning study.Abdominal radiology (New York) · 2026Article
- MS4322 is a selective protein arginine methyltransferase 5 degrader with antitumor effects in cervical cancer cells.Oncology reports · 2026Article
- Preoperative staging of cervical cancer: time to shift from cystoscopy to MRI.European radiology · 2026Article
- IKBIP as a prognostic biomarker and immunotherapeutic target regulates the JAK-STAT3 signaling pathway to promote cervical cancer.Journal of translational medicine · 2026Article
- Assessing long-term quality of life and survivorship priorities in cervical cancer patients: a social media survey-based study.Gynecologic oncology reports · 2026Article
- MicroRNA-628-5p Regulates Proliferation, Apoptosis and Invasion in Hela Cells.Iranian journal of biotechnology · 2026Article
- Quercetin upregulates TLE4 to block the Wnt/β-catenin signaling pathway and inhibit cell migration and invasion of cervical cancer cells.Frontiers in pharmacology · 2026Article
- Recent advancements in the application of artificial intelligence-based approaches for screening, diagnosis, prognosis and treatment of cervical cancer.Oncology reviews · 2026Review
- Impact of laparoscopic versus open surgery on 5-year survival in patients with stage IA2-IB1 cervical cancer: a retrospective cohort study.American journal of cancer research · 2026Article
- Symptom Clusters and Quality of Life in Cervical Cancer Patients During the Perioperative Period: A Longitudinal Study.Patient preference and adherence · 2026Article
- Innate immune recognition and microenvironmental reprogramming in HPV-induced cervical cancer: from pattern recognition receptor activation to immune tolerance disruption.Frontiers in cellular and infection microbiology · 2026Review
- A longitudinal study of early postoperative symptom cluster trajectories in patients with gynecologic malignancies.BMC women's health · 2025Article
- Precision theranostics in cervical Cancer: Harnessing stimuli-responsive hydrogels for tumor microenvironment-targeted therapy and diagnosis.Materials today. Bio · 2025Review
- Integrating neutrophil-to-lymphocyte ratio into cervical cancer management: implications for prognostic assessment and therapeutic strategies - a narrative review.Annals of medicine and surgery (2012) · 2025Review
- Advancing cervical cancer treatment: integrating cannabinoids, combination therapies and nanotechnology.Journal of cancer research and clinical oncology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cervical cancer (CC) remains a public health issue worldwide despite preventive measures. Surgical treatment in the early-stage CC has evolved during the last decades. Our aim was to review the advances in the literature and summarize the ongoing studies on this topic. To this end, we conducted a literature review through PubMed focusing on English-language articles on the surgical management of early-stage CC. The emergent topics considered here are the FIGO 2018 staging system update, conservative management with less radical procedures for selected patients, lymph node staging, fertility preservation, preferred surgical approach, management of tumors up to 2 cm, and prognosis. In terms of updating FIGO, we highlight the inclusion of lymph node status on staging and the possibility of imaging. Regarding the preferred surgical approach, we emphasize the LACC trial impact worldwide in favor of open surgery; however, we discuss the controversial application of this for tumors < 2 cm. In summary, all topics show a tendency to provide patients with tailored treatment that avoids morbidity while maintaining oncologic safety, which is already possible in high-income countries. We believe that efforts should focus on making this a reality for low-income countries as well.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.