Evidence map›Paper›PMID 35158826›Full record

ArticleCancers2022

Outcome of SARS-CoV-2-Infected Polish Patients with Chronic Lymphocytic Leukemia.

Bartosz Puła, Katarzyna Pruszczyk, Ewa Pietrusza, Marta Morawska, Weronika Piszczek, Elżbieta Kalicińska, Agnieszka Szeremet, Jagoda Tryc-Szponder, Ewa Wąsik-Szczepanek, Joanna Drozd-Sokołowska and 15 more

Abstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Review
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  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Bartosz PułaDepartment of Hematology, Institute of Hematology and Transfusion Medicine, 02-776 Warsaw, Poland.
Katarzyna PruszczykDepartment of Hematology, Institute of Hematology and Transfusion Medicine, 02-776 Warsaw, Poland.
Ewa PietruszaMaria Sklodowska-Curie National Research Institute of Oncology, 31-115 Cracow, Poland.
Marta MorawskaExperimental Hematooncology Department, Medical University, 20-400 Lublin, Poland.
Weronika PiszczekDepartment of Hematology, Copernicus Hospital, 87-100 Torun, Poland.
Elżbieta KalicińskaDepartment and Clinic of Hematology, Blood Neoplasms and Bone Marrow Transplantation, Wroclaw Medical University, 52-007 Wroclaw, Poland.
Agnieszka SzeremetDepartment and Clinic of Hematology, Blood Neoplasms and Bone Marrow Transplantation, Wroclaw Medical University, 52-007 Wroclaw, Poland.
Jagoda Tryc-SzponderDepartment of Hematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, 60-569 Poznan, Poland.
Ewa Wąsik-SzczepanekDepartment of Hematooncology and Bone Marrow Transplantation, Medical University, 20-400 Lublin, Poland.
Joanna Drozd-SokołowskaDepartment of Hematology, Transplantation and Internal Medicine, Medical University, 02-097 Warsaw, Poland.ORCID 0000-0002-4562-6264
Helena KrzemieńDepartment of Hematology and Bone Marrow Transplantation, Medical School of Silesia, Silesian Medical University, 40-032 Katowice, Poland.ORCID 0000-0002-8951-4563
Aleksandra RejusDepartment of Hematology, Regional Clinical Hospital No. 1, 35-001 Rzeszow, Poland.ORCID 0000-0003-4239-2834
Małgorzata GajewskaDepartment of Internal Medicine and Hematology, Military Institute of Medicine, 04-141 Warsaw, Poland.ORCID 0000-0002-9035-4042
Kamil WiśniewskiDepartment of Hematology, Institute of Hematology and Transfusion Medicine, 02-776 Warsaw, Poland.ORCID 0000-0003-4164-9343
Maciej WysockiDepartment of Hematology, Institute of Hematology and Transfusion Medicine, 02-776 Warsaw, Poland.
Alan MajeranowskiIntercollegiate Faculty of Biotechnology of the University of Gdansk and the Medical University of Gdansk, 80-307 Gdansk, Poland.
Ewa Paszkiewicz-KozikDepartment of Lymphoid Malignancies, Maria Sklodowska-Curie National Research Institute of Oncology, 00-001 Warsaw, Poland.
Paweł SteckiewiczCollegium Medicum, Jan Kochanowski University, 25-317 Kielce, Poland.ORCID 0000-0001-7234-9410
Łukasz SzukalskiDepartment of Hematology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, 85-168 Bydgoszcz, Poland.ORCID 0000-0002-9885-5140
Łukasz BołkunDepartment of Hematology, Medical University, 15-276 Bialystok, Poland.
Monika Długosz-DaneckaMaria Sklodowska-Curie National Research Institute of Oncology, 31-115 Cracow, Poland.ORCID 0000-0002-8927-4125
Krzysztof GiannopoulosExperimental Hematooncology Department, Medical University, 20-400 Lublin, Poland.ORCID 0000-0003-0135-4030
Krzysztof JamroziakDepartment of Hematology, Transplantation and Internal Medicine, Medical University, 02-097 Warsaw, Poland.
Ewa Lech-MarańdaDepartment of Hematology, Institute of Hematology and Transfusion Medicine, 02-776 Warsaw, Poland.
Iwona HusDepartment of Hematology, Institute of Hematology and Transfusion Medicine, 02-776 Warsaw, Poland.

Funding

Polish Adult Leukemia Group NA
6 · The paper itself

Abstract

backgroundThe severe acute respiratory syndrome coronavirus (SARS-CoV-2) has become the cause of a worldwide pandemic, and its clinical infection course in patients with hematological malignancies may be severe.

methodsWe performed a retrospective study on 188 chronic lymphocytic leukemia patients (CLL) with COVID-19 infection.

resultsAt the time of infection 51 patients (27.1%) were treated with Bruton tyrosine kinase inhibitor (BTKi), 46 (24.5%) with anti-CD20 antibodies while 37 patients (19.7%) received venetoclax. In total, 111 patients (59.0%) required hospitalization and 50 patients (26.5%) died due to COVID-19. Patients with poor performance status (ECOG >1;

conclusionsSARS-CoV-2 infection in CLL patients is associated with poor outcome regardless of administered CLL-directed treatment.

Indexed as

chronic lymphocytic leukemiaCOVID-19infectionprognosisSARS-CoV-2

Identifiers

PMID35158826
PMCPMC8833688

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.