Evidence map›Paper›PMID 35158745›Full record

ArticleCancers2022

Benchmarking Eliminative Radiomic Feature Selection for Head and Neck Lymph Node Classification.

Zoltan R Bardosi, Daniel Dejaco, Matthias Santer, Marcel Kloppenburg, Stephanie Mangesius, Gerlig Widmann, Ute Ganswindt, Gerhard Rumpold, Herbert Riechelmann, Wolfgang Freysinger

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06029777 (Peri-luminal COROnary CTa AI-driven radiOMICS to Identify Vulnerable Patients), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06029777 completednot on this mapstarted 2023, after this paper: background citation

Peri-luminal COROnary CTa AI-driven radiOMICS to Identify Vulnerable Patients

TypeobservationalSponsorIRCCS San RaffaeleRan2023 to 2024Enrolled2,190ConditionsCoronary Artery Disease
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Artificial Intelligence in Head and Neck Surgery.Otolaryngologic clinics of North America · 2024
    Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Zoltan R BardosiDepartment of Otorhinolaryngology-Head and Neck Surgery, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0002-9307-5436
Daniel DejacoDepartment of Otorhinolaryngology-Head and Neck Surgery, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0001-9176-7415
Matthias SanterDepartment of Otorhinolaryngology-Head and Neck Surgery, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Marcel KloppenburgDepartment of Otorhinolaryngology-Head and Neck Surgery, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Stephanie MangesiusDepartment of Radiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0001-5790-2724
Gerlig WidmannDepartment of Radiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0002-7255-0672
Ute GanswindtDepartment of Radiation-Oncology, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0003-4492-614X
Gerhard RumpoldDepartment of Psychiatry, Psychotherapy and Psychosomatics, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Herbert RiechelmannDepartment of Otorhinolaryngology-Head and Neck Surgery, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Wolfgang FreysingerDepartment of Otorhinolaryngology-Head and Neck Surgery, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0002-2833-3224
Innsbruck Medical University · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In head and neck squamous cell carcinoma (HNSCC) pathologic cervical lymph nodes (LN) remain important negative predictors. Current criteria for LN-classification in contrast-enhanced computed-tomography scans (contrast-CT) are shape-based; contrast-CT imagery allows extraction of additional quantitative data ("features"). The data-driven technique to extract, process, and analyze features from contrast-CTs is termed "radiomics". Extracted features from contrast-CTs at various levels are typically redundant and correlated. Current sets of features for LN-classification are too complex for clinical application. Effective eliminative feature selection (EFS) is a crucial preprocessing step to reduce the complexity of sets identified. We aimed at exploring EFS-algorithms for their potential to identify sets of features, which were as small as feasible and yet retained as much accuracy as possible for LN-classification. In this retrospective cohort-study, which adhered to the STROBE guidelines, in total 252 LNs were classified as "non-pathologic" (

Indexed as

computed-tomographyextracapsular spreadfeature extractiongenetic algorithmshead and neck squamous carcinomalymph nodesradiomicsrecursive feature eliminationsparse discriminant analysis

Identifiers

PMID35158745
PMCPMC8833684
OpenAlexW4206337415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.