Evidence map›Paper›PMID 35158418›Full record

ArticleChronic obstructive pulmonary diseases (Miami, Fla.)2022

Treatable Traits in Misdiagnosed Chronic Obstructive Pulmonary Disease: Data from the Akershus Cardiac Examination 1950 Study.

Nina Faksvåg Caspersen, Vidar Søyseth, Magnus Nakrem Lyngbakken, Trygve Berge, Inger Ariansen, Arnljot Tveit, Helge Røsjø, Gunnar Einvik

Registry-linked trialOpen access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chronic obstructive pulmonary diseases (Miami, Fla.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01555411 (Akershus Cardiac Examination 1950 Study - a Cohort Study on Cardio- and Cerebrovascular Disease in 62-65-year-old Subjects), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01555411 active not recruitingnot on this map

Akershus Cardiac Examination 1950 Study - a Cohort Study on Cardio- and Cerebrovascular Disease in 62-65-year-old Subjects

TypeobservationalSponsorVestre Viken Hospital TrustRan2012 to 2050Enrolled3,706ConditionsAtrial Fibrillation, Heart Failure, Mild Cognitive Impairment, Cardiovascular Diseases
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Persistent airway obstruction in severe eosinophilic asthma: targeting interleukin-5 and eosinophils.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  3. The Burden of COPD with Type 2 Inflammation in North-West Continental Europe.International journal of chronic obstructive pulmonary disease · 2025
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Nina Faksvåg CaspersenDivision of Medicine, Akershus University Hospital, Lørenskog, Norway.
Vidar SøysethDivision of Medicine, Akershus University Hospital, Lørenskog, Norway.
Magnus Nakrem LyngbakkenDivision of Medicine, Akershus University Hospital, Lørenskog, Norway.
Trygve BergeDepartment of Medical Research, Bærum Hospital, Vestre Viken Hospital Trust, Gjettum, Norway.
Inger AriansenDivision of Mental and Physical Health, Norwegian Institute of Public Health, Oslo, Norway.
Arnljot TveitInstitute of Clinical Medicine, University of Oslo, Oslo, Norway.
Helge RøsjøInstitute of Clinical Medicine, University of Oslo, Oslo, Norway.
Gunnar EinvikDivision of Medicine, Akershus University Hospital, Lørenskog, Norway.
University of Oslo · NOAkershus University Hospital · NONorwegian Institute of Public Health · NOVestre Viken Hospital Trust · NO

Funding

Akershus University Hospital HFDelphin og hustrus fundExtrastiftelsen 2015/FO7781Trelasthandler AVestre Viken HF
6 · The paper itself

Abstract

backgroundChronic obstructive pulmonary disease (COPD) is often misdiagnosed. We aimed to estimate the prevalence of misdiagnosed COPD in middle-aged Norwegians, and to assess potentially treatable clinical traits in over- and undiagnosed individuals. METHODS AND

findingsThe Akershus Cardiac Examination (ACE) 1950 Study is a population-based study of the 1950 birth cohort of Akershus county including 3706 participants aged 62-65 years at baseline. COPD was defined as a forced expiratory volume in 1 second (FEV

conclusionBoth over- and underdiagnosis of COPD is frequent. Undiagnosed individuals have better lung function and less symptoms, but similar prevalence of comorbidities and systemic inflammation. Overdiagnosed individuals have treatable traits including asthma, eosinophilic inflammation, and sleep apnea. The main predictor of being overdiagnosed was being overweight.

Indexed as

chronic obstructive pulmonary diseasemisdiagnositreatable traits

Identifiers

PMID35158418
PMCPMC9166336
OpenAlexW4213189452

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.