Evidence map›Paper›PMID 35158004›Full record

ArticleThe Journal of arthroplasty2022

Does Blood Flow Restriction Therapy Improve Leg Strength in Patients With a Painful Total Knee Arthroplasty?

Isaac B Majors, Simon C Mears, Christopher K Oholendt, Nicholas A Hargett, C Lowry Barnes, Jeffrey B Stambough

Open access · greenAbstract read
In one paragraph

Article in The Journal of arthroplasty, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Isaac B MajorsDepartment of Orthopaedic Surgery, University of Arkansas for Medical Sciences, Little Rock, AR.
Simon C MearsDepartment of Orthopaedic Surgery, University of Arkansas for Medical Sciences, Little Rock, AR.
Christopher K OholendtUniversity of Arkansas for Medical Sciences, UAMS Reynolds Institute on Aging, Little Rock, AR.
Nicholas A HargettUniversity of Arkansas for Medical Sciences, UAMS Reynolds Institute on Aging, Little Rock, AR.
C Lowry BarnesDepartment of Orthopaedic Surgery, University of Arkansas for Medical Sciences, Little Rock, AR.
Jeffrey B StamboughDepartment of Orthopaedic Surgery, University of Arkansas for Medical Sciences, Little Rock, AR.
University of Arkansas for Medical Sciences · USInstitute on Aging · US

Funding

Understanding the Negative Prognostic Impact of Intraosseous Focal Lesions in Multiple MyelomaP20GM125503 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI Sanja Novak · 2018 to 2026
$23.0M
NIGMS NIH HHS P20 GM125503
6 · The paper itself

Abstract

backgroundBlood flow restriction (BFR) therapy has been proposed to help patients build strength with fewer repetitions than standard physical therapy (PT). We sought to determine if BFR would improve quadriceps and hamstring strength in patients with instability and perceived weakness >1 year after primary total knee arthroplasty (TKA).

methodsWe retrospectively reviewed 48 patients with painful TKAs and flexion instability as well as quadriceps and hamstring weakness who performed a 6-week PT program and received isokinetic strength measurements (ISMs). Thirty-six patients completed a standard PT program (non-BFR) and 12 patients completed a BFR regimen. ISMs were taken before and after PT to quantify quadriceps and hamstring power, torque, and work compared to the contralateral leg. Statistical analysis was conducted on pre-PT and post-PT ISMs and decisions for revision surgery.

resultsThere were no differences in ISMs after PT between the BFR and non-BFR groups. The non-BFR group showed statistically significant strength improvements in flexion but not extension (+28.7%-32.8%, P = .0145-.255). Although no significant difference was found in the BFR group, they saw improvements in all extension strength metrics (19.4%-23.4%, P = .3315-.3901) and flexion (25.7%-29.9%, P = .1994-.2392). No difference was observed between the groups in the rates of subsequent revision TKA (8.3% vs 16.7%, P = .3362).

conclusionBFR did not improve quadriceps and hamstring strength compared to PT alone in patients with instability and weakness after TKA. Over 80% of total patients chose to avoid revision TKA after completion of focused PT with or without BFR.

Indexed as

Arthroplasty, Replacement, KneeBlood Flow Restriction TherapyHumansLegMuscle StrengthPainQuadriceps MuscleRetrospective Studiesblood flow restrictionknee instabilitypainful knee replacementpainful total knee arthroplastyphysical therapystrengthening

Identifiers

PMID35158004
PMCPMC9117439
OpenAlexW4211148005

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.