ArticleJournal of applied clinical medical physics2022
Total workflow uncertainty of frameless radiosurgery with the Gamma Knife Icon cone-beam computed tomography.
Article in Journal of applied clinical medical physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- A multi-institutional survey on radiosurgery for multiple brain metastases in Latin America.Physical and engineering sciences in medicine · 2026Article
- Optimizing anisotropic margins in single-isocenter multiple brain metastases radiosurgery using regressor strategies: A multi-institutional validation study.Journal of applied clinical medical physics · 2025Article
- Feasibility test of 3 dimensional patient specific quality assurance of gamma knife radiosurgery using novel mobile phospor probe system.Scientific reports · 2025Article
- Long-term geometric quality assurance of radiation focal point and cone-beam computed tomography for Gamma Knife radiosurgery system.Radiological physics and technology · 2024Article
- Total workflow uncertainty of frameless radiosurgery with the Gamma Knife Icon cone-beam computed tomography.Journal of applied clinical medical physics · 2022Article
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Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveFrameless treatment with the Gamma Knife Icon is still relatively new as a treatment option. As a result, additional confidence/knowledge about the uncertainty that exists within each portion of the treatment workflow could be gained especially regarding steps that have not been previously studied in the literature.
methodsThe Icon base delivery device (Perfexion) uncertainty is quantified and validated. The novel portions of the Icon such as mask immobilization, cone-beam computed tomography image guidance, and the intrafraction motion management methods are studied specifically and to a greater extent to determine a total workflow uncertainty of frameless treatment with the Icon.
resultsThe uncertainty of each treatment workflow step has been identified with the total workflow uncertainty being identified in this work as 1.3 mm with a standard deviation of 0.51 mm.
conclusionThe total uncertainty of frameless treatment with the Icon has been evaluated and this data may indicate the need for setup margin in this setting with data that could be used by other institutions to calculate needed setup margin per their preferred recipe after validation of this data in their context.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.