Evidence map›Paper›PMID 35157241›Full record

ArticleLa Radiologia medica2022

Diagnostic performance of CT lung severity score and quantitative chest CT for stratification of COVID-19 patients.

Damiano Caruso, Marta Zerunian, Michela Polici, Francesco Pucciarelli, Gisella Guido, Tiziano Polidori, Carlotta Rucci, Benedetta Bracci, Giuseppe Tremamunno, Andrea Laghi

Open access · hybridAbstract read
In one paragraph

Article in La Radiologia medica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Exploring Radiologists' Burnout in the COVID-19 Era: A Narrative Review.International journal of environmental research and public health · 2023
    Review
  8. Review
  9. Gender Medicine in Clinical Radiology Practice.Journal of personalized medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Damiano CarusoDepartment of Medical Surgical Sciences and Translational Medicine, Sapienza University of Rome, Sant'Andrea University Hospital, Via di Grottarossa, 1035-1039, 00189, Rome, Italy.ORCID http://orcid.org/0000-0001-9285-4764
Marta ZerunianDepartment of Medical Surgical Sciences and Translational Medicine, Sapienza University of Rome, Sant'Andrea University Hospital, Via di Grottarossa, 1035-1039, 00189, Rome, Italy.ORCID http://orcid.org/0000-0003-4635-7999
Michela PoliciDepartment of Medical Surgical Sciences and Translational Medicine, Sapienza University of Rome, Sant'Andrea University Hospital, Via di Grottarossa, 1035-1039, 00189, Rome, Italy.ORCID http://orcid.org/0000-0001-7331-6901
Francesco PucciarelliDepartment of Medical Surgical Sciences and Translational Medicine, Sapienza University of Rome, Sant'Andrea University Hospital, Via di Grottarossa, 1035-1039, 00189, Rome, Italy.ORCID http://orcid.org/0000-0001-7263-1125
Gisella GuidoDepartment of Medical Surgical Sciences and Translational Medicine, Sapienza University of Rome, Sant'Andrea University Hospital, Via di Grottarossa, 1035-1039, 00189, Rome, Italy.ORCID http://orcid.org/0000-0002-0711-2975
Tiziano PolidoriDepartment of Medical Surgical Sciences and Translational Medicine, Sapienza University of Rome, Sant'Andrea University Hospital, Via di Grottarossa, 1035-1039, 00189, Rome, Italy.ORCID http://orcid.org/0000-0002-4633-6760
Carlotta RucciDepartment of Medical Surgical Sciences and Translational Medicine, Sapienza University of Rome, Sant'Andrea University Hospital, Via di Grottarossa, 1035-1039, 00189, Rome, Italy.ORCID http://orcid.org/0000-0003-3793-2277
Benedetta BracciDepartment of Medical Surgical Sciences and Translational Medicine, Sapienza University of Rome, Sant'Andrea University Hospital, Via di Grottarossa, 1035-1039, 00189, Rome, Italy.ORCID http://orcid.org/0000-0002-2017-8493
Giuseppe TremamunnoDepartment of Medical Surgical Sciences and Translational Medicine, Sapienza University of Rome, Sant'Andrea University Hospital, Via di Grottarossa, 1035-1039, 00189, Rome, Italy.ORCID http://orcid.org/0000-0001-6484-9765
Andrea LaghiDepartment of Medical Surgical Sciences and Translational Medicine, Sapienza University of Rome, Sant'Andrea University Hospital, Via di Grottarossa, 1035-1039, 00189, Rome, Italy. andrea.laghi@uniroma1.it.ORCID http://orcid.org/0000-0002-3091-7819
Sapienza University of Rome · ITAzienda Ospedaliera Sant'Andrea · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLung severity score (LSS) and quantitative chest CT (QCCT) analysis could have a relevant impact to stratify patients affected by COVID-19 pneumonia at the hospital admission. The study aims to assess LSS and QCCT performances in severity stratification of COVID-19 patients. MATERIALS AND

methodsFrom April 19, 2020, until May 3, 2020, patients with chest CT suggestive for interstitial pneumonia and tested positive for COVID-19 were retrospectively enrolled and stratified for hospital admission as Group 1, 2 and 3 (home isolation, low intensive care and intensive care, respectively). For LSS, lungs were divided in 20 regions and visually assessed by two radiologists who scored for each region from non-lung involvement as 0, < 50% assigned as 1 and > 50% as 2. QCCT was performed with a dedicated software that extracts pulmonary involvement expressed in liters and percentage. LSS and QCCT were analyzed with ROC curve analysis to predict the performance of both methods. P values < 0.05 were considered statistically significant.

resultsFinal population enrolled included 136 patients (87 males, mean age 66 ± 16), 19 patients in Group 1, 86 in Group 2 and 31 in Group 3. Significant differences for LSS were observed in almost all comparisons, especially in Group 1 vs 3 (AUC 0.850, P < 0,0001) and Group 1 + 2 vs 3 (AUC 0.783, P < 0,0001). QCCT showed significant results in almost all comparisons, especially between Group 1 vs 3 (AUC 0.869, P < 0,0001). LSS and QCCT comparison between Group 1 and Group 2 did not show significant differences.

conclusionsLSS and QCCT could represent promising tools to stratify COVID-19 patient severity at the admission.

Indexed as

COVID-19AgedAged, 80 and overHumansLungMaleMiddle AgedRetrospective StudiesSARS-CoV-2Tomography, X-Ray ComputedChest CTCOVID-19Lung quantificationLung severity scoreSeverity stratification

Identifiers

PMID35157241
PMCPMC8852873
OpenAlexW4212766587

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.