Evidence map›Paper›PMID 35157237›Full record

ReviewCurrent diabetes reports2022

The Diabetes-Cardiovascular Connection in Women: Understanding the Known Risks, Outcomes, and Implications for Care.

Eric K Broni, Chiadi E Ndumele, Justin B Echouffo-Tcheugui, Rita R Kalyani, Wendy L Bennett, Erin D Michos

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current diabetes reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Eric K BroniDepartment of Medicine, Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Chiadi E NdumeleDepartment of Medicine, Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Justin B Echouffo-TcheuguiDepartment of Medicine, Division of Endocrinology, Diabetes & Metabolism, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Rita R KalyaniDepartment of Medicine, Division of Endocrinology, Diabetes & Metabolism, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Wendy L BennettDivision of General Internal Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Erin D MichosDepartment of Medicine, Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD, USA. edonnell@jhmi.edu.
Johns Hopkins Medicine · USJohns Hopkins University · US

Funding

The Effect of Sex Hormones on Cardiometabolic Outcomes in Men and Women with Diabetes: The Look AHEAD (Action for Health in Diabetes) StudyR01DK127222 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI BENNETT, WENDY LYNET, VAIDYA, DHANANJAY MADHUKAR · 2020 to 2024
$2.5M
Establishing the Pathways Between Diabetes and Cardiac Dysfunction: Epidemiology, Biomarkers, and ImagingK23HL153774 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI ECHOUFFO TCHEUGUI, JUSTIN BASILE · 2020 to 2024
$991k
American Heart Association 20SFRN35120152American Heart Association 874772NHLBI NIH HHS K23 HL153774NIDDK NIH HHS R01 DK127222
6 · The paper itself

Abstract

purpose of reviewCardiovascular disease (CVD) complications constitute about 50-70% of mortality in people with diabetes. However, there remains a persistently greater relative increase in CVD morbidity and mortality in women with diabetes than in their male counterparts. This review presents recent evidence for the risks, outcomes, and management implications for women with diabetes. RECENT

findingsCompared to men, women have higher BMI and more adverse cardiovascular risk profile at time of diabetes diagnosis with greater risk for coronary heart disease, stroke, vascular dementia, and heart failure. Pregnancy-specific risk factors of gestational diabetes and pre-eclampsia are associated with future type 2 diabetes (T2D) and CVD. Women with T2D may experience greater benefits than men from GLP-1 receptor agonists. Women with diabetes are at greater relative risk for CVD complications than men, with poorer outcomes, superimposed on preexisting gender disparities in social determinants of health, lower likelihood of being offered cardioprotective interventions, and enrollment in trials. Further research and the utilization of SGLT-2 inhibitors, GLP-1 receptor agonists, and other CVD prevention strategies will help reduce morbidity and mortality.

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2FemaleGlucagon-Like Peptide-1 Receptor AgonistsHumansMalePregnancyRisk AssessmentRisk FactorsGlucagon-Like Peptide-1 Receptor AgonistsCardiovascular diseasesDiabetesGestational diabetesMenopauseObesityPolycystic ovary syndrome

Identifiers

PMID35157237
OpenAlexW4213038363

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.