ArticleMarine biotechnology (New York, N.Y.)2022
Ocean Acidification Alters Developmental Timing and Gene Expression of Ion Transport Proteins During Larval Development in Resilient and Susceptible Lineages of the Pacific Oyster (Crassostrea gigas).
Article in Marine biotechnology (New York, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 12 citations in OpenAlex.
- Transcriptome-To-Phenome Response of Larval Eastern Oysters Under Multiple Drivers of Aragonite Undersaturation.Ecology and evolution · 2025Article
- Investigating the Mechanism of Low-Salinity Environmental Adaptation inAnimals : an open access journal from MDPI · 2023Article
- RNAi Silencing of the Biomineralization Gene Perlucin Impairs Oyster Ability to Cope with Ocean Acidification.International journal of molecular sciences · 2023Article
- Impacts of Seawater pH Buffering on the Larval Microbiome and Carry-Over Effects on Later-Life Disease Susceptibility in Pacific Oysters.Applied and environmental microbiology · 2022Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Ocean acidification (OA) adversely impacts initial shell formation of bivalve larvae. Despite many studies observing large differences in developmental success between distinct genetic populations of bivalves exposed to OA, few studies have investigated the molecular mechanisms that enable resilient larvae to build their initial shell in aragonite-undersaturated conditions. This knowledge is key to their ecological and economical conservation. Herein, we used a genetic-selection program for Crassostrea gigas to produce a resilient and susceptible larval lineage to OA. The resilient and susceptible larvae were sampled every 3 h over a 24-h period in aragonite-undersaturated and control conditions. The susceptible lineage failed to develop a larval shell in aragonite-undersaturated conditions, whereas 52% of the resilient lineage developed to D-larvae by 24 h post fertilisation. We measured the expression of 23 genes involved in initial shell formation by RT-qPCR, which revealed significant genotype-by-time and environment-by-time interactions for the transcription of these genes. Aragonite-undersaturated conditions upregulated a single gene encoding a protein involved in ion transport, Na
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