Evidence map›Paper›PMID 35157137›Full record

ArticleJournal of neurology2022

Delirium on stroke units: a prospective, multicentric quality-improvement project.

Peter Nydahl, Friederike Baumgarte, Daniela Berg, Manuela Bergjan, Christoph Borzikowsky, Christiana Franke, Diana Green, Anisa Hannig, Hans Christian Hansen, Armin Hauss and 14 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Nursing workload during delirium: a systematic literature review.Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2025
    Pooled it
  2. Risk factors for delirium after hip arthroplasty: An umbrella meta-analysis.International journal of nursing studies advances · 2026
    Review
  3. Prevention and Treatment of ICU Delirium in Brain Injured Patients.Current neurology and neuroscience reports · 2026
    Review
  4. Risk-predicting and screening tools of post-stroke delirium: a narrative review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Review
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  12. Associations between early in-hospital medications and the development of delirium in patients with stroke.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 6 institutions in 3 countries.

Peter NydahlNursing Science and development, Department of Anesthesiology and Intensive Care Medicine, University Hospital of Schleswig-Holstein, Kiel, Germany. Peter.Nydahl@uksh.de.ORCID http://orcid.org/0000-0002-5178-0364
Friederike BaumgarteChristian Albrechts University Kiel, Kiel, Germany.
Daniela BergDepartment of Neurology, University Hospital of Schleswig-Holstein, Kiel, Germany.
Manuela BergjanBusiness Division Nursing Directorate, Nursing Science, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.ORCID http://orcid.org/0000-0002-3786-3104
Christoph BorzikowskyInstitute of Medical Informatics und Statistics, University Hospital of Schleswig-Holstein, Kiel, Germany.
Christiana FrankeDepartment of Neurology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.ORCID http://orcid.org/0000-0002-5609-2472
Diana GreenChristian Albrechts University Kiel, Kiel, Germany.
Anisa HannigDepartment of Neurology, Friedrich-Ebert-Krankenhaus, Neumünster, Germany.
Hans Christian HansenDepartment of Neurology, Friedrich-Ebert-Krankenhaus, Neumünster, Germany.
Armin HaussBusiness Division Nursing Directorate, Nursing Science, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.ORCID http://orcid.org/0000-0003-3666-4127
Uta HansenDepartment of Neurology, Diako Flensburg, Flensburg, Germany.
Rahel IstelChristian Albrechts University Kiel, Kiel, Germany.
Norma KrämerDepartment of Neurology, Friedrich-Ebert-Krankenhaus, Neumünster, Germany.
Karita KrauseChristian Albrechts University Kiel, Kiel, Germany.
Renée LohrmannBusiness Division Nursing Directorate, Nursing Science, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.ORCID http://orcid.org/0000-0002-8264-8745
Mohammad Mohammadzadeh-VazifehDepartment of Neurology, Friedrich-Ebert-Krankenhaus, Neumünster, Germany.
Jürgen OsterbrinkInstitut für Pflegewissenschaft und-praxis, Paracelsus Medizinische Privatuniversität, Salzburg, Austria.
Frederick PalmDepartment of Neurology, Heliosklinikum Schleswig, Schleswig, Germany.
Telse PetersenChristian Albrechts University Kiel, Kiel, Germany.
Bernd SchöllerDepartment of Neurology, Heliosklinikum Schleswig, Schleswig, Germany.
Henning StolzeDepartment of Neurology, Diako Flensburg, Flensburg, Germany.
Max ZilezinskiBusiness Division Nursing Directorate, Nursing Science, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.ORCID http://orcid.org/0000-0001-9225-1672
Johannes MeyneDepartment of Neurology, University Hospital of Schleswig-Holstein, Kiel, Germany.
Nils G MargrafDepartment of Neurology, University Hospital of Schleswig-Holstein, Kiel, Germany.
Christian-Albrechts-Universität zu Kiel · DEHumboldt-Universität zu Berlin · DEUniversity Hospital Schleswig-Holstein · DEFriedrich-Ebert-Krankenhaus · DEDIAKO · DEUniversity of North Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPost-stroke delirium (POD) in patients on stroke units (SU) is associated with an increased risk for complications and poorer clinical outcome. The objective was to reduce the severity of POD by implementing an interprofessional delirium-management.

methodsMulticentric quality-improvement project on five SU implementing a delirium-management with pre/post-comparison. Primary outcome was severity of POD, assessed with the Nursing Delirium Screening Scale (Nu-DESC). Secondary outcome parameters were POD incidence, duration, modified Rankin Scale (mRS), length of stay in SU and hospital, mortality, and others.

resultsOut of a total of 799 patients, 59.4% (n = 475) could be included with 9.5% (n = 45) being delirious. Implementation of a delirium-management led to reduced POD severity; Nu-DESC median: pre: 3.5 (interquartile range 2.6-4.7) vs. post 3.0 (2.2-4.0), albeit not significant (p = 0.154). Other outcome parameters were not meaningful different. In the post-period, delirium-management could be delivered to 75% (n = 18) of delirious patients, and only 24 (53.3%) of delirious patients required pharmacological treatments. Patients with a more severe stroke and POD remained on their disability levels, compared to similar affected, non-delirious patients who improved.

conclusionsImplementation of delirium-management on SU is feasible and can be delivered to most patients, but with limited effects. Nursing interventions as first choice could be delivered to the majority of patients, and only the half required pharmacological treatments. Delirium-management may lead to reduced severity of POD but had only partial effects on duration of POD or length of stay. POD hampers rehabilitation, especially in patients with more severe stroke. REGISTRY: DRKS, DRKS00021436. Registered 04/17/2020, www.drks.de/DRKS00021436 .

Indexed as

DeliriumStrokeHumansIncidencePostoperative ComplicationsProspective StudiesQuality ImprovementRegistriesRisk FactorsDeliriumEncephalopathyQuality-improvementStroke

Identifiers

PMID35157137
PMCPMC9217833
OpenAlexW4213235481

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.