Evidence map›Paper›PMID 35157073›Full record

ReviewInteractive cardiovascular and thoracic surgery2022

Ventilatory efficiency slope is associated with cardiopulmonary complications after thoracoscopic anatomical lung resection.

Benoît Bédat, Evangelos Koliakos, Marco S Demarchi, Jean Perentes, Marc-Joseph Licker, Frédéric Triponez, Thorsten Krueger, Wolfram Karenovics, Michel Gonzalez

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Interactive cardiovascular and thoracic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Benoît BédatService of Thoracic Surgery, University Hospital of Lausanne, Lausanne, Switzerland.ORCID 0000-0002-3758-7867
Evangelos KoliakosService of Thoracic Surgery, University Hospital of Lausanne, Lausanne, Switzerland.
Marco S DemarchiDivision of Thoracic and Endocrine Surgery, Geneva University Hospitals and University of Geneva, Geneva, Switzerland.
Jean PerentesService of Thoracic Surgery, University Hospital of Lausanne, Lausanne, Switzerland.
Marc-Joseph LickerDivision of Anesthesiology, Geneva University Hospitals and University of Geneva, Geneva, Switzerland.
Frédéric TriponezDivision of Thoracic and Endocrine Surgery, Geneva University Hospitals and University of Geneva, Geneva, Switzerland.ORCID 0000-0001-7808-496X
Thorsten KruegerService of Thoracic Surgery, University Hospital of Lausanne, Lausanne, Switzerland.
Wolfram KarenovicsDivision of Thoracic and Endocrine Surgery, Geneva University Hospitals and University of Geneva, Geneva, Switzerland.
Michel GonzalezService of Thoracic Surgery, University Hospital of Lausanne, Lausanne, Switzerland.ORCID 0000-0001-8705-4279

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to identify whether steeper V.E/V. CO2 slope was associated with cardiopulmonary complications (CPC) after anatomical resection by video-assisted thoracic surgery. Long-term survival was analysed as secondary outcome.

methodsWe reviewed the files of all consecutive patients who underwent pulmonary anatomical resections by video-assisted thoracic surgery between January 2010 and October 2020 at the Centre for Thoracic Surgery of Western Switzerland. Logistic regression was used to investigate the risk of CPC associated with the V.E/V.CO2 slope and other possible confounders. Survival was analysed with Kaplan-Meier curves. Risk factors associated with survival were analysed with a Cox proportional hazards model.

resultsThe V.E/V.CO2 slope data were available for 145 patients [F/M: 66/79; mean age (standard deviation): 65.8 (8.9)], which were included in the analysis. Patients underwent anatomical resection [lobectomy (71%) or segmentectomy (29%)] mainly for lung cancer (96%). CPC and all-cause 90-day mortality were 29% and 1%, respectively. The mean (standard deviation) percentage of the predicted V.O2peak was 70% (17). Maximum effort during cardiopulmonary exercise test was reached in only 31% of patients. The V.E/V.CO2 slope (standard deviation) was not different if the maximum effort was reached or not [39 (6) vs 37 (7), P = 0.21]. V.E/V.CO2 slope >35 was associated with an increased risk of CPC (odds ratio 2.9, 95% confidence interval 1.2, 7.2, P = 0.020). V.E/V.CO2 slope >35 was not associated with shorter survival censored for lung cancer-related death.

conclusionsV . E/V.CO2 slope >35 is significantly associated with postoperative CPC after anatomical resections by video-assisted thoracic surgery. CLINICAL REGISTRATION NUMBER CER-VD (SWITZERLAND): Project ID: 2021-00620.

Indexed as

Lung NeoplasmsPneumonectomyCarbon DioxideHumansLungPostoperative ComplicationsRetrospective StudiesThoracic Surgery, Video-AssistedCarbon DioxideAnatomical lung resectionLung cancerMinute ventilation-to-carbon dioxide output slopePostoperative complicationsVentilatory efficiencyVideo-assisted thoracic surgery

Identifiers

PMID35157073
PMCPMC9252121

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.