Evidence map›Paper›PMID 35156881›Full record

ArticleBiodemography and social biology

Financial strain moderates genetic influences on self-rated health: support for diathesis-stress model of gene-environment interplay.

Deborah Finkel, Catalina Zavala, Carol E Franz, Shandell Pahlen, Margaret Gatz, Nancy L Pedersen, Brian K Finch, Anna Dahl Aslan, Vibeke S Catts, Malin Ericsson and 6 more

Abstract read
In one paragraph

Article in Biodemography and social biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. The Interplay of Genes and Environment Across Multiple Studies (IGEMS) Consortium After Fifteen Years.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2026
    Article
  3. Article
  4. Article
  5. Genetic and environmental influences on alcohol consumption in middle to late life.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025
    Article
  6. Observational
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Deborah FinkelDepartment of Psychology, Indiana University Southeast, New Albany, Indiana.ORCID 0000-0003-2346-2470
Catalina ZavalaDepartment of Psychology, University of Southern California, Los Angeles, California.
Carol E FranzDepartment of Psychology, University of California, San Diego, California.
Shandell PahlenDepartment of Psychology, University of California, Riverside, California.
Margaret GatzCenter for Economic and Social Research, University of Southern California, Los Angeles, California.ORCID 0000-0002-1071-9970
Nancy L PedersenDepartment of Psychology, University of Southern California, Los Angeles, California.ORCID 0000-0001-8057-3543
Brian K FinchDepartment of Sociology and Spatial Sciences, University of Southern California, Los Angeles, California.
Anna Dahl AslanInstitute of Gerontology and Aging Research Network-Jönköping (ARN-J), Jönköping University, Jönköping, Sweden.
Vibeke S CattsCentre for Healthy Brain Ageing, School of Psychiatry, Faculty of Medicine, UNSW Sydney, Kensington, Australia.
Malin EricssonDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden.
Robert F KruegerDepartment of Psychology, University of Minnesota, Minneapolis, Minnesota.
Nicholas G MartinGenetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
Adith MohanCentre for Healthy Brain Ageing, School of Psychiatry, Faculty of Medicine, UNSW Sydney, Kensington, Australia.
Miriam A MosingDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden.
Carol A PrescottDepartment of Psychology, University of Southern California, Los Angeles, California.
Keith E WhitfieldDepartment of Psychology, University of Nevada Las Vegas, Las Vegas, Nevada.

Funding

The VETSA Longitudinal MRI Twin Study of AgingR01AG022381 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KREMEN, WILLIAM S. · 2003 to 2019
$22.3M
The VETSA Longitudinal Twin Study of Cognition and AgingR01AG018384 · NIA · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI LYONS, MICHAEL J. · 2002 to 2012
$9.8M
The VETSA longitudinal twin study of cognition and agingR01AG018386 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KREMEN, WILLIAM S. · 2002 to 2012
$9.7M
Risk for Alzheimer's Disease and Cognitive Decline in Project TALENTR01AG056163 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PRESCOTT, CAROL ARLENE · 2016 to 2020
$5.4M
Sex differences in the relationship between APOE and AD: Role of sexual differentiationRF1AG058068 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GATZ, MARGARET, LADU, MARY JO · 2017 to 2017
$3.8M
Clarifying risk and protective factors for dementia with the Interplay of Genes and Environment in Multiple Studies (IGEMS) consortiumR01AG060470 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GATZ, MARGARET, PEDERSEN, NANCY L · 2018 to 2022
$3.6M
Gene-Environment Interplay of Social Contexts and Aging-Related OutcomesR01AG037985 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PEDERSEN, NANCY L · 2010 to 2014
$3.2M
SES health gradients in late life: testing models of gene-environment interplay in an international twin consortiumR01AG059329 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FINCH, BRIAN K., GATZ, MARGARET · 2018 to 2022
$2.9M
The VETSA Longitudinal Twin Study of Cortisol and AgingR01AG022982 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KREMEN, WILLIAM S. · 2004 to 2007
$2.6M
A 55-Year Follow-up Study of Project TALENT Twins and Siblings R01AG043656 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PRESCOTT, CAROL ARLENE · 2013 to 2014
$923k
Gene-Environment Interplay of Social Contexts and Aging-Related OutcomesR56AG037985 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GATZ, MARGARET, PEDERSEN, NANCY L · 2016 to 2016
$818k
NIA NIH HHS R01 AG018384NIA NIH HHS R01 AG018386NIA NIH HHS R01 AG022381NIA NIH HHS R01 AG022982NIA NIH HHS R01 AG037985NIA NIH HHS R01 AG043656NIA NIH HHS R01 AG056163NIA NIH HHS R01 AG059329NIA NIH HHS R01 AG060470NIA NIH HHS R56 AG037985NIA NIH HHS RF1 AG058068
6 · The paper itself

Abstract

Data from the Interplay of Genes and Environment across Multiple Studies (IGEMS) consortium were used to examine predictions of different models of gene-by-environment interaction to understand how genetic variance in self-rated health (SRH) varies at different levels of financial strain. A total of 11,359 individuals from 10 twin studies in Australia, Sweden, and the United States contributed relevant data, including 2,074 monozygotic and 2,623 dizygotic twin pairs. Age ranged from 22 to 98 years, with a mean age of 61.05 (SD = 13.24). A factor model was used to create a harmonized measure of financial strain across studies and items. Twin analyses of genetic and environmental variance for SRH incorporating age, age

Indexed as

Twins, DizygoticAdultAgedAged, 80 and overDisease SusceptibilityHumansMiddle AgedSwedenUnited StatesYoung Adult

Identifiers

PMID35156881
PMCPMC9038652

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.