ArticleThe FEBS journal2022
Probing heavy metal binding to phycobiliproteins.
Article in The FEBS journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- Red Seaweed-Derived Phycobiliproteins: Marine Bioactive Colorants with Functional Health Properties.Marine drugs · 2026Review
- Algal and Cyanobacteria Cell Walls as Biosorbents for Phenolic Compounds: Comparative Performance and Sustainability Assessment ofBioengineering (Basel, Switzerland) · 2026Article
- Mass spectrometry reveals the evolutionary conservation of phycobiliprotein complexes.Nature communications · 2026Article
- Heterogeneity within phycobilisomes is highly orchestrated.Photosynthesis research · 2026Article
- Determination of Trace Cu(II) Ions Using a Siraitia Grosvenorii Residue-derived Nitrogen-doped Carbon Dots-enabled Fluorescence Quenching Sensor.Journal of fluorescence · 2026Article
- Phycobiliproteins of Marine Red Alga, Kappaphycus Alvarezii Possess Potent Antioxidant and Metal Chelating Properties, and Inhibit Hepatocellular Carcinoma (HepG2) Cell Growth.Applied biochemistry and biotechnology · 2026Article
- Intracellular vesicle-mediated biomineralization of arsenic and barium by a sponge symbiotic bacterium.ISME communications · 2026Article
- Use of Enriched Mine Water to Grow the CyanobacteriumFoods (Basel, Switzerland) · 2025Article
- Evidencing nickel biosorption capacity of cyanobacteria Chroococcidiopsis sp.: potential metallo-protective agents.BMC chemistry · 2025Article
- Determination of Heavy Metal Content: Arsenic, Cadmium, Mercury, and Lead in Cyano-Phycocyanin Isolated from the Cyanobacterial Biomass.Plants (Basel, Switzerland) · 2023Article
- The increasing role of structural proteomics in cyanobacteria.Essays in biochemistry · 2023Review
- Assessment of Metal Accumulation byMicroorganisms · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Blue-green algae, also known as cyanobacteria, contain some of the most efficient light-harvesting complexes known. These large, colourful complexes consist of phycobiliproteins which are extremely valuable in the cosmetics, food, nutraceutical and pharmaceutical industries. Additionally, the colourful and fluorescent properties of phycobiliproteins can be modulated by metal ions, making them highly attractive as heavy metal sensors and heavy metal scavengers. Although the overall quenching ability metal ions have on phycobiliproteins is known, the mechanism of heavy metal binding to phycobiliproteins is not fully understood, limiting their widespread quantitative applications. Here, we show using high-resolution native mass spectrometry that phycobiliprotein complexes bind metal ions in different manners. Through monitoring the binding equilibria and metal-binding stoichiometry, we show in particular copper and silver to have drastic, yet different effects on phycobiliprotein structure, both copper and silver modulate the overall complex properties. Together, the data reveals the mechanisms by which metal ions can modulate phycobiliprotein properties which can be used as a basis for the future design of metal-related phycobiliprotein applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.