Evidence map›Paper›PMID 35156622›Full record

ArticleEuropean journal of rheumatology2022

Early impacts of the COVID-19 pandemic on children with pediatric rheumatic diseases.

Jonathan S Hausmann, Kevin Kennedy, Salman Surangiwala, Maggie J Larche, Rashmi Sinha, Karen Durrant, Gary Foster, Mitchell Levine, Lehana Thabane, Wendy Costello and 4 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of rheumatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 3 countries.

Jonathan S HausmannProgram in Rheumatology, Division of Immunology, Boston Children's Hospital, Boston, MA, USA; Division of Rheumatology and Clinical Immunology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Kevin KennedyDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
Salman SurangiwalaQueen's University School of Medicine, Kingston, ON, Canada.
Maggie J LarcheDivisions of Rheumatology/Clinical Immunology and Allergy, Department of Medicine, McMaster University, Hamilton, ON, Canada.
Rashmi SinhaSystemic JIA Foundation, Cincinnati, OH, USA.
Karen DurrantAutoinflammatory Alliance, San Francisco, CA, USA.
Gary FosterDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
Mitchell LevineDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
Lehana ThabaneDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
Wendy CostelloIrish Children's Arthritis Network (iCAN), Tipperary, Ireland.
Philip C RobinsonSchool of Clinical Medicine, Faculty of Medicine, University of Queensland, Queensland, Australia.
Jean W LiewSection of Rheumatology, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
Jinoos YazdanyDivision of Rheumatology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.
Emily SirotichDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada; Canadian Arthritis Patient Alliance, Toronto, ON, Canada.
Impact · CABoston University · USThe University of Queensland · AUBoston Children's Hospital · USCanadian Arthritis Patient Alliance · CADigital Research Alliance of CanadaMcMaster University Medical Centre · CAQueen's University · CAUniversity of California, San Francisco · US

Funding

RESOURCE-BASED CENTER FOR THE ADVANCEMENT OF PRECISION MEDICINE IN RHEUMATOLOGYP30AR070155 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Mary C Nakamura · 2016 to 2026
$8.2M
Advancing Quality and Outcomes Measurement in RheumatologyK24AR074534 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Jinoos Yazdany · 2019 to 2026
$1.5M
NIAMS NIH HHS K24 AR074534NIAMS NIH HHS P30 AR070155
6 · The paper itself

Abstract

objectivesThe experiences of children with pediatric rheumatic diseases (PRD) during the initial phase of the COVID-19 pandemic have not been well-documented. We sought to determine the effects of the COVID-19 pandemic on protective behaviors, healthcare access, medication management, and education among an international cross-sectional parental survey of children with PRDs.

methodsThe COVID-19 Global Rheumatology Alliance Patient Experience Survey was distributed online, and parents of children with parental-reported PRD, with or without COVID-19 infection, were eligible to enroll. Respondents described their child's demographics, adoptions of protective behaviors, healthcare access, changes to immunosuppression, and disruptions in schooling.

resultsA total of 427 children were included in the analyses. The most common rheumatic disease was juvenile idiopathic arthritis (40.7%), and most children were taking conventional synthetic diseasemodifying antirheumatic drugs (DMARDs) (54.6%) and/or biologic DMARDs (51.8%). A diagnosis of COVID-19 was reported in five children (1.2%), none of whom required hospitalization. Seventeen children (4.0%) had stopped or delayed their drugs due to concern for immunosuppression, most commonly glucocorticoids. Almost all families adopted behaviors to protect their children from COVID-19, including quarantining, reported by 96.0% of participants. In addition, 98.3% of full-time students experienced disruptions in their education, including cancelations of classes and transitions to virtual classrooms.

conclusionDespite the low numbers of children with PRDs who developed COVID-19 in this cohort, most experienced significant disruptions in their daily lives, including quarantining and interruptions in their education. The drastic changes to these children's environments on their future mental and physical health and development remain unknown.

Identifiers

PMID35156622
PMCPMC12462871
OpenAlexW4210574389

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.