ArticleJournal of the American Heart Association2022
Open access · goldAbstract read
In one paragraph
Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
11.7field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 71 citations in OpenAlex.
- CYP2C19 Genotyping to Guide Clopidogrel Prescribing for Neurovascular Indications: A Survey of Institutional Approaches.Clinical pharmacology and therapeutics · 2026Article
- Bridging the Gap Between Pharmacogenomic Discovery and Clinical Implementation: Insights from Selected Studies on Inter-Individual Variability in Drug Response.Journal of personalized medicine · 2026Article
- Precision percutaneous coronary intervention.NPJ cardiovascular health · 2026Review
- Development and validation of a clinical-pharmacogenomic prediction model for clopidogrel-related high on-treatment platelet reactivity in patients with coronary artery disease.Frontiers in cardiovascular medicine · 2026Article
- A feasibility study of whole genome germline testing as an adjunct screening tool in a UK general private practice.Scientific reports · 2025Article
- CYP2C19 Polymorphisms and Clinical Outcomes Following Percutaneous Coronary Intervention in the Million Veteran Program.Clinical pharmacology and therapeutics · 2025Article
- Assessing Impact of Concomitant Use of Proton Pump Inhibitors and Clopidogrel on Incidence of Major Adverse Cardiovascular Events: A Retrospective Cohort Study.Pharmacoepidemiology and drug safety · 2025Article
- Efficacy and safety of clopidogrel and ticagrelor in acute coronary syndrome patients withResearch and practice in thrombosis and haemostasis · 2025Article
- Article
- The Pharmacogenomics Global Research Network Implementation Working Group: global collaboration to advance pharmacogenetic implementation.Pharmacogenetics and genomics · 2025Article
- Pharmacogenetics: Opportunities for theAnnual review of pharmacology and toxicology · 2025Review
- Pharmacovigilance processes in low- and middle-income countries: moving from data collection to data analysis and interpretation.Therapeutic advances in drug safety · 2025Article
- CYP2C19 Genotype-Guided Antiplatelet Therapy and Clinical Outcomes in Patients Undergoing a Neurointerventional Procedure.Clinical and translational science · 2025Review
- Multi-Omics Research on Angina Pectoris: A Novel Perspective.Aging and disease · 2024Review
- Association ofBalkan journal of medical genetics : BJMG · 2024Article
- Breaking boundaries: Ticagrelor monotherapy in high-risk patients.International journal of cardiology. Heart & vasculature · 2024Review
- Observational Analyses of Ex Vivo Native American Platelet Responses.International journal of molecular sciences · 2024Observational
- Genetic Determinants of Response to P2YInterventional cardiology clinics · 2024Review
- Genotype-Guided Antiplatelet Therapy: JACC Review Topic of the Week.Journal of the American College of Cardiology · 2024Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
25 authors at 10 institutions in 1 country.
Amber L BeitelsheesDepartment of Medicine and Program for Personalized and Genomic Medicine University of Maryland School of Medicine Baltimore MD.ORCID 0000-0003-0958-7197
Cameron D ThomasDepartment of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine University of Florida College of Pharmacy Gainesville FL.
Philip E EmpeyDepartment of Pharmacy and Therapeutics University of Pittsburgh School of Pharmacy Pittsburgh PA.ORCID 0000-0001-7474-2339
George A StoufferDivision of Cardiology and McAllister Heart Institute University of North Carolina, Chapel Hill NC.ORCID 0000-0001-8208-8998
Dominick J AngiolilloUniversity of Florida College of Medicine-Jacksonville Jacksonville FL.ORCID 0000-0001-8451-2131
Francesco FranchiUniversity of Florida College of Medicine-Jacksonville Jacksonville FL.
Sony TutejaUniversity of Pennsylvania Perelman School of Medicine Philadelphia PA.ORCID 0000-0001-7007-3289
Nita A LimdiDepartment of Neurology Program for Translational Pharmacogenomics and Hugh Kaul Personalized Medicine Institute School of Medicine University of Alabama at Birmingham AL.
James C LeeDepartment of Pharmacy Practice University of Illinois at Chicago IL.ORCID 0000-0002-3101-7281
Julio D DuarteDepartment of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine University of Florida College of Pharmacy Gainesville FL.ORCID 0000-0001-9766-4038
Rolf P KreutzIndiana University School of Medicine Indianapolis IN.ORCID 0000-0002-2110-607X
Todd C SkaarIndiana University School of Medicine Indianapolis IN.
James C CoonsDepartment of Pharmacy and Therapeutics University of Pittsburgh School of Pharmacy Pittsburgh PA.ORCID 0000-0002-7193-3751
Jay GiriCardiovascular Medicine Division University of Pennsylvania Perelman School of Medicine Philadelphia PA.ORCID 0000-0002-8076-0098
Caitrin W McDonoughDepartment of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine University of Florida College of Pharmacy Gainesville FL.
Rachel RowlandDepartment of Medicine and Program for Personalized and Genomic Medicine University of Maryland School of Medicine Baltimore MD.
James M StevensonDepartment of Pharmacy and Therapeutics University of Pittsburgh School of Pharmacy Pittsburgh PA.ORCID 0000-0003-1640-1135
Thuy ThaiDepartment of Pharmaceutical Outcomes & Policy and Center for Drug Evaluation and Safety University of Florida Gainesville FL.ORCID 0000-0003-4544-1160
Mark R VeselyDepartment of Medicine and Program for Personalized and Genomic Medicine University of Maryland School of Medicine Baltimore MD.ORCID 0000-0002-6817-5515
Jacob T WellenDepartment of Medicine and Program for Personalized and Genomic Medicine University of Maryland School of Medicine Baltimore MD.
Julie A JohnsonDepartment of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine University of Florida College of Pharmacy Gainesville FL.
Almut G WintersteinDepartment of Pharmaceutical Outcomes & Policy and Center for Drug Evaluation and Safety University of Florida Gainesville FL.ORCID 0000-0002-6518-5961
Larisa H CavallariDepartment of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine University of Florida College of Pharmacy Gainesville FL.
Craig R LeeDivision of Cardiology and McAllister Heart Institute University of North Carolina, Chapel Hill NC.ORCID 0000-0003-3595-5301
Implementing Genomics in Practice (IGNITE) Network Pharmacogenetics Working Group
University of Florida · USUniversity of Maryland, Baltimore · USCenter for Drug Evaluation and Research · USIndiana University School of MedicineUniversity of North Carolina at Chapel Hill · USUniversity of Pennsylvania · USUniversity of Pittsburgh · USJohns Hopkins University · USUniversity of Alabama at Birmingham · USUniversity of Illinois Chicago · US
Funding
University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8MRe-Entry Supplement: Investigation of Oral Microbial Enzymes for the Detection and Treatment of Periodontal DiseaseUL1TR002489 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, SHAHEEN, NICHOLAS J · 2018 to 2022
$48.6MUsing social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2MPharmacogenomic Evaluation of Antihypertensive ResponsesU01GM074492 · NIGMS · UNIVERSITY OF FLORIDA · PI COOPER-DEHOFF, RHONDA M, JOHNSON, JULIE A. · 2005 to 2014
$20.7MSparking Advancements in Genomic MedicineU01HG007269 · NHGRI · UNIVERSITY OF FLORIDA · PI CAVALLARI, LARISA HUMMA, JOHNSON, JULIE A. · 2013 to 2024
$17.0MPharmacogenomics of Anti-platlet Intervention-2 (PAPI-2) StudyU01HL105198 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI SHULDINER, ALAN R. · 2010 to 2014
$13.6MUF Clinical and Translational Science AwardUL1TR000064 · NCATS · UNIVERSITY OF FLORIDA · PI NELSON, DAVID R · 2012 to 2014
$12.2MPredictors of hemorrhage among patients on direct acting oral anticoagulantsR01HL092173 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LIMDI, NITA A · 2008 to 2023
$10.4MUAB Center for Clinical and Translational Science (CCTS) UL1UL1TR000165 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KIMBERLY, ROBERT P. · 2012 to 2013
$9.6MAfrican American Cardiovascular pharmacogenetic CONsorTium (ACCOuNT): discovery and translationU54MD010723 · NIMHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MELTZER, DAVID O, PERERA, MINOLI A · 2016 to 2020
$9.5MImplementing genomic medicine through pragmatic trials in diverse and underserved populations across Indiana.U01HG010245 · NHGRI · INDIANA UNIVERSITY INDIANAPOLIS · PI DEXTER, PAUL, SKAAR, TODD C. · 2018 to 2024
$9.4MEmbedding Pharmacogenotyping in an Integrated Health System for the UnderservedU01HG007762 · NHGRI · INDIANA UNIVERSITY INDIANAPOLIS · PI DEXTER, PAUL, SKAAR, TODD C. · 2014 to 2018
$4.4MNCATS NIH HHS UL1 TR000005NCATS NIH HHS UL1 TR000064NCATS NIH HHS UL1 TR000165NCATS NIH HHS UL1 TR001427NCATS NIH HHS UL1 TR002489NHGRI NIH HHS T32 HG008958NHGRI NIH HHS U01 HG007269NHGRI NIH HHS U01 HG007762NHGRI NIH HHS U01 HG007775NHGRI NIH HHS U01 HG010245NHLBI NIH HHS K01 HL141690NHLBI NIH HHS K23 HL143161NHLBI NIH HHS K24 HL133373NHLBI NIH HHS R01 HL092173NHLBI NIH HHS R01 HL149752NHLBI NIH HHS U01 HL105198NIGMS NIH HHS U01 GM074492NIMHD NIH HHS U54 MD010723
Abstract
Background Studies have demonstrated increased risk of major atherothrombotic events in
Indexed as
Percutaneous Coronary InterventionPlatelet Aggregation InhibitorsClopidogrelCytochrome P-450 CYP2C19GenotypeHumansTreatment OutcomeClopidogrelCYP2C19 protein, humanCytochrome P-450 CYP2C19Platelet Aggregation InhibitorsclopidogrelCYP2C19pharmacogenetics
Identifiers
What OpenQuestion holds
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LicenceCC BY-NC-ND
Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.