ArticleTropical medicine & international health : TM & IH2022
Framing the detection of incipient tuberculosis infection: A qualitative study of political prioritisation.
Article in Tropical medicine & international health : TM & IH, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Biomarker tests of progression from tuberculosis infection to disease: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2026Pooled it
- Exploring HIV provider framings of living and aging with HIV.SSM. Qualitative research in health · 2025Article
- Framing the detection of incipient tuberculosis infection: A qualitative study of political prioritisation.Tropical medicine & international health : TM & IH · 2022Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveIncipient Tuberculosis (ITB) refers to Mycobacterium tuberculosis infection that is likely to progress to active disease in the absence of treatment, but without clinical signs, symptoms, radiographic or microbiological evidence of disease. Biomarker-based tests to diagnose incipient TB hold promise for better prediction and, through TB preventive therapy, prevention of disease. This study explored current and future framing and prioritisation of ITB.
methodsTwenty-two interviews across eight countries were conducted. A modified Shiffman & Smith Framework, containing four categories-Ideas, Issue Characteristics, Actor Power, and Political Contexts-was used to analyse the current landscape and potential for prioritisation of diagnosis and treatment of ITB.
resultsLatent TB policy implementation has been slow due to technical, logistical and financial challenges, and because it has been framed in a manner non-conducive to gaining political priority. Framing ITB testing as 'early detection' rather than 'prediction', and its management as 'treatment' rather than 'preventive therapy', may help raise its importance in policies, and its acceptance among actors.
conclusionConsensus surrounding the framing of ITB will be crucial for the successful adoption of ITB diagnostics and treatment. When designing ITB tools and policies, it will be important to address challenges that pertain to latent TB policies.
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