Evidence map›Paper›PMID 35156270›Full record

ArticleNeurogastroenterology and motility2022

Standardized system and App for continuous patient symptom logging in gastroduodenal disorders: Design, implementation, and validation.

Gabrielle Sebaratnam, Nikita Karulkar, Stefan Calder, Jonathan S T Woodhead, Celia Keane, Daniel A Carson, Chris Varghese, Peng Du, Stephen J Waite, Jan Tack and 4 more

Abstract read
In one paragraph

Article in Neurogastroenterology and motility, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Next generation of gastrointestinal electrophysiology devices.Nature reviews. Gastroenterology & hepatology · 2024
    Article
  20. Effect of menstrual cycle and menopause on human gastric electrophysiology.American journal of physiology. Gastrointestinal and liver physiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Gabrielle SebaratnamThe University of Auckland, Auckland, New Zealand.ORCID 0000-0002-9946-9815
Nikita KarulkarThe University of Auckland, Auckland, New Zealand.ORCID 0000-0001-9177-0382
Stefan CalderThe University of Auckland, Auckland, New Zealand.ORCID 0000-0002-5855-1732
Jonathan S T WoodheadAlimetry Ltd, Auckland, New Zealand.
Celia KeaneThe University of Auckland, Auckland, New Zealand.ORCID 0000-0002-9611-2335
Daniel A CarsonThe University of Auckland, Auckland, New Zealand.ORCID 0000-0002-5089-2807
Chris VargheseThe University of Auckland, Auckland, New Zealand.ORCID 0000-0001-7369-8639
Peng DuThe University of Auckland, Auckland, New Zealand.ORCID 0000-0002-6913-7545
Stephen J WaiteAlimetry Ltd, Auckland, New Zealand.ORCID 0000-0002-2856-0566
Jan TackDepartment of Gastroenterology, University Hospitals, Leuven, Belgium.ORCID 0000-0002-3206-6704
Christopher N AndrewsAlimetry Ltd, Auckland, New Zealand.
Elizabeth BroadbentThe University of Auckland, Auckland, New Zealand.ORCID 0000-0003-3626-9100
Armen A GharibansThe University of Auckland, Auckland, New Zealand.ORCID 0000-0002-9139-4740
Greg O'GradyThe University of Auckland, Auckland, New Zealand.ORCID 0000-0002-5998-1080

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFunctional gastroduodenal disorders include functional dyspepsia, chronic nausea and vomiting syndromes, and gastroparesis. These disorders are common, but their overlapping symptomatology poses challenges to diagnosis, research, and therapy. This study aimed to introduce and validate a standardized patient symptom-logging system and App to aid in the accurate reporting of gastroduodenal symptoms for clinical and research applications.

methodsThe system was implemented in an iOS App including pictographic symptom illustrations, and two validation studies were conducted. To assess convergent and concurrent validity, a diverse cohort with chronic gastroduodenal symptoms undertook App-based symptom logging for 4 h after a test meal. Individual and total post-prandial symptom scores were averaged and correlated against two previously validated instruments: PAGI-SYM (for convergent validity) and PAGI-QOL (for concurrent validity). To assess face and content validity, semi-structured qualitative interviews were conducted with patients. KEY

resultsApp-based symptom reporting demonstrated robust convergent validity with PAGI-SYM measures of nausea (r CONCLUSIONS AND INFERENCES: The continuous patient symptom-logging App demonstrated robust convergent, concurrent, face, and content validity when used within a 4-h post-prandial test protocol. The App will enable standardized symptom reporting and is anticipated to provide utility in both research and clinical practice.

Indexed as

Duodenal DiseasesGastroparesisMobile ApplicationsGastric EmptyingHumansNauseaQuality of LifeSeverity of Illness IndexSurveys and Questionnaireschronic nausea and vomiting syndromedigital healthfunctional disordersfunctional gastrointestinal disordersgastroparesisgut-brain-axis

Identifiers

PMID35156270
PMCPMC9541247

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.