Evidence map›Paper›PMID 35156075›Full record

ArticleLancet regional health. Americas2022

Seroprevalence of anti-SARS-CoV-2 antibodies in Colombia, 2020: A population-based study.

Marcela Mercado-Reyes, Jeadran Malagón-Rojas, Isabel Rodríguez-Barraquer, Silvana Zapata-Bedoya, Magdalena Wiesner, Zulma Cucunubá, Yesith Guillermo Toloza-Pérez, Juan P Hernández-Ortiz, Jorge Acosta-Reyes, Eliana Parra-Barrera and 19 more

Open access · goldAbstract read
In one paragraph

Article in Lancet regional health. Americas, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

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  16. Environmental Effects of the COVID-19 Pandemic: The Experience of Bogotá, 2020.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 8 institutions in 3 countries.

Marcela Mercado-ReyesInstituto Nacional de Salud, Avenida Calle 26 51 -20, Bogotá, Colombia.
Jeadran Malagón-RojasInstituto Nacional de Salud, Avenida Calle 26 51 -20, Bogotá, Colombia.
Isabel Rodríguez-BarraquerUniversity of California, San Francisco, CA, USA.
Silvana Zapata-BedoyaInstituto Nacional de Salud, Avenida Calle 26 51 -20, Bogotá, Colombia.
Magdalena WiesnerInstituto Nacional de Salud, Avenida Calle 26 51 -20, Bogotá, Colombia.
Zulma CucunubáImperial College London, London, UK.
Yesith Guillermo Toloza-PérezInstituto Nacional de Salud, Avenida Calle 26 51 -20, Bogotá, Colombia.
Juan P Hernández-OrtizUniversidad Nacional de Colombia, Medellin, Antioquia, Colombia.
Jorge Acosta-ReyesSchool of Medicine, Universidad del Norte de Barranquilla, Barranquilla, Colombia.
Eliana Parra-BarreraInstituto Nacional de Salud, Avenida Calle 26 51 -20, Bogotá, Colombia.
Edgar Ibáñez-BeltránInstituto Nacional de Salud, Avenida Calle 26 51 -20, Bogotá, Colombia.
Gianni G QuincheInstituto Nacional de Salud, Avenida Calle 26 51 -20, Bogotá, Colombia.
Lyda Muñoz-GalindoInstituto Nacional de Salud, Avenida Calle 26 51 -20, Bogotá, Colombia.
Vivian RubioInstituto Nacional de Salud, Avenida Calle 26 51 -20, Bogotá, Colombia.
Marisol Galindo-BordaInstituto Nacional de Salud, Avenida Calle 26 51 -20, Bogotá, Colombia.
Erickson G Osorio-VelázquezDepartamento Administrativo Nacional de Estadística - DANE, Bogotá, Colombia.
Andrea Bermúdez-ForeroInstituto Nacional de Salud, Avenida Calle 26 51 -20, Bogotá, Colombia.
Nelson Pinto-ChacónInstituto Nacional de Salud, Avenida Calle 26 51 -20, Bogotá, Colombia.
Gloria Puerto-CastroInstituto Nacional de Salud, Avenida Calle 26 51 -20, Bogotá, Colombia.
Carlos Franco-MuñozInstituto Nacional de Salud, Avenida Calle 26 51 -20, Bogotá, Colombia.
María Isabel EstupiñanCentro de Atención y Diagnóstico de Enfermedades Infecciosas - CDI, Bucaramanga, Colombia.
Luis Ángel VillarCentro de Atención y Diagnóstico de Enfermedades Infecciosas - CDI, Bucaramanga, Colombia.
Nancy Gore-SaraviaCentro Internacional de Entrenamiento e Investigaciones Medicas - CIDEIM, Cali, Colombia.
María Consuelo Miranda-MontoyaCentro Internacional de Entrenamiento e Investigaciones Medicas - CIDEIM, Cali, Colombia.
Jaime CastellanosUniversidad El Bosque, Bogotá, Colombia.
Edna Margarita ValleDepartamento Administrativo Nacional de Estadística - DANE, Bogotá, Colombia.
Edgar Navarro-LechugaSchool of Medicine, Universidad del Norte de Barranquilla, Barranquilla, Colombia.
Juan Daniel OviedoDepartamento Administrativo Nacional de Estadística - DANE, Bogotá, Colombia.
Martha Ospina-MartínezInstituto Nacional de Salud, Avenida Calle 26 51 -20, Bogotá, Colombia.
Instituto Nacional de Salud · COUniversidad Nacional de Colombia · COCentro Internacional de Entrenamiento e Investigaciones Medicas · COColciencias · COUniversidad del Norte · COImperial College London · GBUniversidad El Bosque · COUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to cause very high morbidity and mortality throughout Latin American countries. However, few population-based seroprevalence surveys have been conducted to quantify attack rates and characterize drivers of transmission.

methodsWe conducted a population-based cross-sectional study to assess the seroprevalence of antibodies against SARS-CoV-2 in ten cities in Colombia between September and December 2020. The study involved multi-stage cluster sampling at each city. Participants provided a serum sample and answered a demographic and risk factor questionnaire. Prior infection by SARS-CoV-2 was ascertained using the "SARS-CoV-2 Total (COV2T) Advia Centaur - Siemens" chemiluminescence assay.

findingsA total of 17863 participants from 7320 households participated in the study. Seroprevalence varied substantially between cities, ranging from 26% (95%CI 23-29 %) in Medellín to 68% (95%CI 62-74 %) in Guapi. There were no differences in seroprevalence by sex, but seropositivity was higher in certain ethnic groups. There was substantial heterogeneity in seroprevalence within cities, driven to a large extent by a strong association between socioeconomic stratum and seropositivity.

interpretationColombia has been one of the Latin American countries most affected by the COVID-19 pandemic. This study documented very high attack rates in several Colombian cities by the end of 2020 and identified key drivers of heterogeneities including ethnicity and socioeconomic stratum. Few studies of seroprevalence of SARS-CoV-2 have been conducted in Latin America, and therefore this study contributes to the fundamental understanding of the pandemic in the region.

fundingThe study was sponsored by, Ministerio de Ciencia y Tecnología e Innovación -CT361/2020, Ministerio de Salud y Protección Social, Fundación Universitaria del Norte, Imperial College of London, Universidad Nacional de Colombia (Sede Medellín), Universidad de Córdoba, California University, Unidad Nacional de Gestión del Riesgo, Centro de Atención y Diagnóstico de Enfermedades Infecciosas -CDI-, Centro Internacional de Entrenamiento e Investigaciones Médicas -CIDEIM-, Departamento Administrativo Nacional de Estadística - DANE, Fondo Nacional de Turismo -FONTUR-, Secretarías de Salud Departamentales, Distritales y Municipales and Instituto Nacional de Salud.

Indexed as

ColombiaCOVID-19PopulationPublic healthSARS-CoV-2Seroprevalence

Identifiers

PMID35156075
PMCPMC8817632
OpenAlexW4213389360

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.