Evidence map›Paper›PMID 35155994›Full record

ArticleJMIR infodemiology

Misinformation About and Interest in Chlorine Dioxide During the COVID-19 Pandemic in Mexico Identified Using Google Trends Data: Infodemiology Study.

Jonathan Matias Chejfec-Ciociano, Juan Pablo Martínez-Herrera, Alexa Darianna Parra-Guerra, Ricardo Chejfec, Francisco José Barbosa-Camacho, Juan Carlos Ibarrola-Peña, Gabino Cervantes-Guevara, Guillermo Alonso Cervantes-Cardona, Clotilde Fuentes-Orozco, Enrique Cervantes-Pérez and 2 more

Open access · goldAbstract read
In one paragraph

Article in JMIR infodemiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Chlorine Dioxide: Friend or Foe for Cell Biomolecules? A Chemical Approach.International journal of molecular sciences · 2022
    Review
  4. Article
  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Jonathan Matias Chejfec-CiocianoUnidad de Investigación Biomédica 02 Hospital de Especialidades del Centro Médico Nacional de Occidente Instituto Mexicano del Seguro Social Guadalajara Mexico.ORCID https://orcid.org/0000-0003-0205-6844
Juan Pablo Martínez-HerreraUnidad de Investigación Biomédica 02 Hospital de Especialidades del Centro Médico Nacional de Occidente Instituto Mexicano del Seguro Social Guadalajara Mexico.ORCID https://orcid.org/0000-0003-2243-9391
Alexa Darianna Parra-GuerraUnidad de Investigación Biomédica 02 Hospital de Especialidades del Centro Médico Nacional de Occidente Instituto Mexicano del Seguro Social Guadalajara Mexico.ORCID https://orcid.org/0000-0001-5833-9849
Ricardo ChejfecMax Bell School of Public Policy McGill University Montreal, QC Canada.ORCID https://orcid.org/0000-0002-9477-1943
Francisco José Barbosa-CamachoUnidad de Investigación Biomédica 02 Hospital de Especialidades del Centro Médico Nacional de Occidente Instituto Mexicano del Seguro Social Guadalajara Mexico.ORCID https://orcid.org/0000-0002-3897-2767
Juan Carlos Ibarrola-PeñaUnidad de Investigación Biomédica 02 Hospital de Especialidades del Centro Médico Nacional de Occidente Instituto Mexicano del Seguro Social Guadalajara Mexico.ORCID https://orcid.org/0000-0003-4271-7512
Gabino Cervantes-GuevaraHospital Civil de Guadalajara "Fray Antonio Alcalde" Universidad de Guadalajara Guadalajara Mexico.ORCID https://orcid.org/0000-0001-6249-4737
Guillermo Alonso Cervantes-CardonaDepartamento de Disciplinas Filosófico, Metodológicas e Instrumentales Centro Universitario de Ciencias de la Salud Universidad de Guadalajara Guadalajara Mexico.ORCID https://orcid.org/0000-0003-0180-6201
Clotilde Fuentes-OrozcoUnidad de Investigación Biomédica 02 Hospital de Especialidades del Centro Médico Nacional de Occidente Instituto Mexicano del Seguro Social Guadalajara Mexico.ORCID https://orcid.org/0000-0001-6230-8359
Enrique Cervantes-PérezDepartamento de Nutriología Clínica Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán" Ciudad de Mexico Mexico.ORCID https://orcid.org/0000-0002-6333-9082
Benjamín García-ReynaCentro Universitario del Norte Universidad de Guadalajara Colotlan Mexico.ORCID https://orcid.org/0000-0001-8649-9831
Alejandro González-OjedaUnidad de Investigación Biomédica 02 Hospital de Especialidades del Centro Médico Nacional de Occidente Instituto Mexicano del Seguro Social Guadalajara Mexico.ORCID https://orcid.org/0000-0003-2935-8703
Mexican Social Security Institute · MXUniversidad de Guadalajara · MXInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán · MXMcGill University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe COVID-19 pandemic has prompted the increasing popularity of several emerging therapies or preventives that lack scientific evidence or go against medical directives. One such therapy involves the consumption of chlorine dioxide, which is commonly used in the cleaning industry and is available commercially as a mineral solution. This substance has been promoted as a preventive or treatment agent for several diseases, including SARS-CoV-2 infection. As interest in chlorine dioxide has grown since the start of the pandemic, health agencies, institutions, and organizations worldwide have tried to discourage and restrict the consumption of this substance.

objectiveThe aim of this study is to analyze search engine trends in Mexico to evaluate changes in public interest in chlorine dioxide since the beginning of the COVID-19 pandemic.

methodsWe retrieved public query data for the Spanish equivalent of the term "chlorine dioxide" from the Google Trends platform. The location was set to Mexico, and the time frame was from March 3, 2019, to February 21, 2021. A descriptive analysis was performed. The Kruskal-Wallis and Dunn tests were used to identify significant changes in search volumes for this term between four consecutive time periods, each of 13 weeks, from March 1, 2020, to February 27, 2021.

resultsFrom the start of the pandemic in Mexico (February 2020), an upward trend was observed in the number of searches compared with that in 2019. Maximum volume trends were recorded during the week of July 19-25, 2020. The search volumes declined between September and November 2020, but another peak was registered in December 2020 through February 2021, which reached a maximum value on January 10. Percentage change from the first to the fourth time periods was +312.85, -71.35, and +228.18, respectively. Pairwise comparisons using the Kruskal-Wallis and Dunn tests showed significant differences between the four periods (

conclusionsMisinformation is a public health risk because it can lower compliance with the recommended measures and encourage the use of therapies that have not been proven safe. The ingestion of chlorine dioxide presents a danger to the population, and several adverse reactions have been reported. Programs should be implemented to direct those interested in this substance to accurate medical information.

Indexed as

chlorine dioxidecoronavirusCOVID-19COVID-19 misinformationdigital epidemiologyGoogle Trendsinfodemiologyinternetinternet behaviormHealthmobile healthpandemicpublic health surveillancetele-epidemiology

Identifiers

PMID35155994
PMCPMC8805460
OpenAlexW4205324194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.