Evidence map›Paper›PMID 35155869›Full record

ArticleKidney international reports2022

Three-Year Clinical Outcomes of the First South Asian Prospective Longitudinal Observational IgA Nephropathy Cohort.

Suceena Alexander, Santosh Varughese, Rajanbabu Franklin, Grace Rebekah, Sanjeet Roy, Sabina Yusuf, Athul Thomas, Jeethu Joseph Eapen, Elenjickal Elias John, Anna T Valson and 5 more

Open access · goldAbstract read
In one paragraph

Article in Kidney international reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 4 countries.

Suceena AlexanderDepartment of Nephrology, Christian Medical College, Vellore, India.
Santosh VarugheseDepartment of Nephrology, Christian Medical College, Vellore, India.
Rajanbabu FranklinDepartment of Nephrology, Christian Medical College, Vellore, India.
Grace RebekahDepartment of Biostatistics, Christian Medical College, Vellore, India.
Sanjeet RoyDepartment of General Pathology, Christian Medical College, Vellore, India.
Sabina YusufDepartment of Nephrology, Christian Medical College, Vellore, India.
Athul ThomasDepartment of Nephrology, Christian Medical College, Vellore, India.
Jeethu Joseph EapenDepartment of Nephrology, Christian Medical College, Vellore, India.
Elenjickal Elias JohnDepartment of Nephrology, Christian Medical College, Vellore, India.
Anna T ValsonDepartment of Nephrology, Christian Medical College, Vellore, India.
Vinoi George DavidDepartment of Nephrology, Christian Medical College, Vellore, India.
Mohamed R DahaUniversity Medical Center Groningen, Groningen, The Netherlands.
John FeehallyCollege of Medicine Biological Sciences and Psychology, University of Leicester, Leicester, UK.
Jonathan BarrattCollege of Medicine Biological Sciences and Psychology, University of Leicester, Leicester, UK.
George T JohnDepartment of Nephrology, Christian Medical College, Vellore, India.
Christian Medical College, Vellore · INUniversity of Leicester · GBUniversity Medical Center Groningen · NL

Funding

DBT-Wellcome Trust India Alliance IA/CPHE/14/1/501501Wellcome Trust
6 · The paper itself

Abstract

introductionGlomerular Research And Clinical Experiments-IgA Nephropathy in Indians (GRACE-IgANI) is the first prospective South Asian IgA nephropathy (IgAN) cohort with prespecified objectives, protocolized longitudinal follow-up, and extensive biosample collection. The baseline risk scores predicted high risk of kidney disease progression.

methodsA total of 195 of 201 patients (97%) completed 3-year follow-up in September 2020. All patients received optimized supportive care, and those at high risk of progression were offered systemic corticosteroids.

resultsA total of 76 patients (76 of 193, 39.4%) had rapid progression in 3 years (≥5 ml/min per 1.73 m

conclusionWe identified longitudinal clinical variables measured at 6 months and ≥5 ml/min per 1.73 m

Indexed as

ACE inhibitorsglomerulonephritisIgA nephropathynephrotic syndromeproteinuriarenal pathology

Identifiers

PMID35155869
PMCPMC8820995
OpenAlexW3217162256

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.