ArticleKidney international reports2022
Increasing Incidence of Inadequate Kidney Biopsy Samples Over Time: A 16-Year Retrospective Analysis From a Large National Renal Biopsy Laboratory.
Article in Kidney international reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Effect of Preprocedural Desmopressin on Complications after Kidney Biopsy: A Systematic Review and Meta-Analysis.Kidney360 · 2026Pooled it
- Comparison of outcomes of an 18-gauge vs 16-gauge ultrasound-guided percutaneous renal biopsy: a systematic review and meta-analysis.Renal failure · 2023Pooled it
- Cranial versus Caudal Direction Technique of Native Percutaneous Kidney Biopsy: A Randomized Controlled Trial.International journal of nephrology and renovascular disease · 2023Trial
- Adequacy and safety of pediatric native kidney biopsy using 16- and 18-gauge needles.Pediatric nephrology (Berlin, Germany) · 2026Article
- Association of Histological Features of Cortical and Medullary Peritubular Capillaries With Progressive CKD.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2026Article
- Diagnostic Performance of [Diagnostics (Basel, Switzerland) · 2026Article
- Balancing Glomerular Adequacy and Bleeding Risk in Native Kidney Biopsy: A Multicenter Cohort Study of Multiple Needle Passes.Kidney medicine · 2026Article
- Performing a percutaneous kidney biopsy.World journal of nephrology · 2026Review
- Preprocedural Anxiety in Kidney Biopsy: A Prospective Study of Prevalence, Risk Factors, and Physiological Correlates.Journal of clinical medicine · 2026Article
- Kidney biopsy in the diagnosis of immunoglobulin A nephropathy.Frontiers in medicine · 2026Article
- Tangential biopsy angle and needle depth for adequacy and safety outcomes in ultrasound-guided native kidney biopsy-a single-center experience in a high-risk population.Journal of nephrology · 2025Article
- A Comprehensive Assessment of Plasma CXCL9 and CXCL10 in Improving Clinical Prediction Models for Kidney Allograft Rejection.Clinical transplantation · 2025Article
- Podocyte extracellular vesicles and immune mediators as urinary biomarkers in active lupus nephritis.Scientific reports · 2025Article
- Machine Learning for Monoclonal Gammopathies of Renal Significance Risk Stratification Using Clinical and Pathology Data.Kidney international reports · 2025Article
- Smartphone-based machine learning model for real-time assessment of medical kidney biopsy.Journal of pathology informatics · 2024Article
- Pilot Study of a Web-Based Tool for Real-Time Adequacy Assessment of Kidney Biopsies.Kidney international reports · 2024Article
- Pathologic Spectrum of Kidney Diseases Within Very Elderly Patients who Underwent Kidney Biopsy.Kidney international reports · 2024Article
- Fibrosis in Chronic Kidney Disease: Pathophysiology and Therapeutic Targets.Journal of clinical medicine · 2024Review
- Factors Associated with Glomerular Yield in Percutaneous Kidney Biopsy.Journal of clinical medicine · 2023Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionRenal biopsy remains an essential tool for the diagnosis and treatment of patients with medical kidney disease. Recently, there has been a perceived change in the number of inadequate samples. The aim of this study was to determine the native renal biopsy miss rate from 2005 to 2020 at Arkana Laboratories, a nationwide kidney biopsy service.
methodsFrom 2005 to 2020, a total of 123,372 native kidney biopsies were received from >2500 nephrologists practicing across 44 US states. The miss rate was determined by age and year. In a subset of biopsies received in 2005 and 2018, the biopsy operator was determined, nephrologist or radiologist. Furthermore, the miss rate, needle gauge, biopsy depth by operator, and biopsy core width by gauge were measured.
resultsThe miss rate increased markedly from 2% in 2005 to 14% in 2020. Radiologists performed 5% of biopsies in 2005 and 95% in 2018 using smaller diameter (18g/20g) needles 92% of the time. Glomeruli per centimeter of core biopsy and mean core width were significantly lower with smaller needles. The miss rate deep was significantly lower for nephrologists and remained consistent within operator between the 2 time points. The miss rate did not correlate with the increasing age of the population who had biopsies.
conclusionThis increase in kidney biopsy miss rate significantly affects patient care in the management of medical kidney disease. Its correlation with the complete reversal in operators suggests an urgent need for interaction with and training of radiologists in this critical technique.
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